PMID: 9180110Jun 1, 1997Paper

A reappraisal of exercise electrocardiographic indexes of the severity of ischemic heart disease: angiographic and scintigraphic correlates

Journal of the American College of Cardiology
P BogatyG R Dagenais

Abstract

We explored how the exercise electrocardiographic (ECG) indexes generally presumed to signify severe ischemic heart disease (IHD) correlate with coronary angiographic and scintigraphic myocardial perfusion findings. In exercise testing, it is generally assumed that the early onset of ST segment depression and its occurrence at a low rate-pressure product (ischemic threshold); the amount of maximal ST segment depression; and a horizontal or downsloping ST segment and its prolonged recovery after exercise signify more severe IHD. However, the relation of these indexes to coronary angiographic and exercise myocardial perfusion findings in patients with IHD is unclear. We prospectively carried out a symptom-limited 12-lead Bruce protocol thallium-201 single-photon emission computed tomographic (SPECT) exercise test in 66 consecutive subjects with stable angina, > or = 70% stenosis of at least one coronary artery, normal rest ECG and left ventricular wall motion and a prior positive exercise ECG. The above ECG indexes, vessel disease (VD), a VD score and the quantitative thallium-SPECT measures of the extent, maximal deficit and redistribution gradient of the perfusion abnormality were characterized. Maximal ST segment depression co...Continue Reading

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Citations

May 28, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Stefano MuzzarelliMichael Johannes Zellweger
Jun 15, 2011·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Saurabh MalhotraPrem Soman
Mar 28, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Nikant K SabharwalAvijit Lahiri
Sep 11, 2007·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Jonathan W WeinsaftMassimiliano Szulc
Jul 30, 1999·The American Journal of Cardiology·M E Tavel, C Shaar
Dec 7, 2002·International Journal of Cardiology·Milind Y DesaiFinn Mannting
Feb 24, 2001·Journal of the American College of Cardiology·P BogatyG R Dagenais
Dec 6, 2007·The Canadian Journal of Cardiology·Gilles R DagenaisAndré Moisan
Sep 6, 2008·Journal of the American College of Cardiology·Demosthenes G Katritsis, Bernhard Meier
Nov 9, 2005·The American Journal of Cardiology·Jonathan W WeinsaftPaul Kligfield
Mar 27, 2013·IEEE Transactions on Medical Imaging·Bjørn Fredrik NielsenPer Grøttum
Oct 18, 2008·American Heart Journal·Peter BogatyGilles R Dagenais

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