A recently identified ovine Babesia in China: serology and sero-epidemiology

Parasitology International
Guiquan GuanJianxun Luo

Abstract

Babesia sp. in Xinjiang, transmitted by Hyalomma, is a large Babesia that is infective for small ruminants, but it has almost no pathogenicity in healthy sheep. On the basis of the sequences of the 18S rRNA and internal transcribed spacer (ITS) genes, morphological characteristics, vector tick species and pathogenicity it was identified recently as a novel Babesia species. In the present study, an enzyme-linked immunosorbent assay (ELISA) was developed using soluble merozoite antigens of Babesia sp. in Xinjiang (BXJMA) derived from in vitro culture. When the positive threshold was chosen as 24.65% of the specific mean antibody rate, the specificity and sensitivity were both 97.3%. There was no cross-reaction between BXJMA and positive sera from sheep infected with other Chinese ovine piroplasms or Anaplasma ovis in the ELISA and western blotting. Specific antibodies against Babesia sp. in Xinjiang could be detected 2 weeks post infection and a high level of antibodies persisted for more than 12 weeks in experimentally infected sheep. The ELISA was tested on 3857 sera collected from small ruminants in 50 prefectures of 22 provinces to evaluate the sero-epidemiology of Babesia sp. in Xinjiang infection, and the average positive r...Continue Reading

References

Dec 1, 1981·Veterinary Parasitology·D Christensson, E Thunegard
Sep 1, 1995·Parasite : Journal De La Société Française De Parasitologie·A ChauvinA Gorenflot
Mar 21, 1998·Preventive Veterinary Medicine·J B MolloyR J Dalgliesh
Jun 1, 2005·Veterinary Parasitology·Q LiuY Fu
Jan 19, 2008·Parasitology Research·Hong Yin, Jianxun Luo
May 23, 2009·Experimental Parasitology·Guiquan GuanHong Yin
Jan 27, 2010·Experimental & Applied Acarology·Ze ChenJingze Liu

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Citations

Mar 16, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Qingli NiuHong Yin
Aug 9, 2012·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Leonhard SchnittgerDavid A Morrison
Jan 31, 2017·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Qingli NiuHong Yin
Jan 29, 2020·Veterinary Parasitology·Onur Ceylan, Ferda Sevinc
Sep 11, 2021·Parasites & Vectors·Jinming WangHong Yin
Sep 7, 2021·Frontiers in Cellular and Infection Microbiology·Jinming WangGuiquan Guan

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