PMID: 11309146Apr 20, 2001Paper

A recessive mutation in the Arabidopsis SSI2 gene confers SA- and NPR1-independent expression of PR genes and resistance against bacterial and oomycete pathogens

The Plant Journal : for Cell and Molecular Biology
J ShahD F Klessig

Abstract

The Arabidopsis thaliana NPR1 gene is required for salicylic acid (SA)-induced expression of pathogenesis-related (PR) genes and systemic acquired resistance. However, loss-of-function mutations in NPR1 do not confer complete loss of PR gene expression or disease resistance. Thus these responses also can be activated via an NPR1-independent pathway that currently remain to be elucidated. The ssi2-1 mutant, identified in a genetic screen for suppressors of npr1-5, affects signaling through the NPR1-independent defense pathway(s). In comparison with the wild-type (SSI2 NPR1) plants and the npr1-5 mutant (SSI2 npr1-5), the ssi2-1 npr1-5 double mutant and the ssi2-1 NPR1 single mutant constitutively express PR genes [PR-1, BGL2 (PR-2) and PR-5]; accumulate elevated levels of SA; spontaneously develop lesions; and possess enhanced resistance to a virulent strain of Peronospora parasitica. The ssi2-1 mutation also confers enhanced resistance to Pseudomonas syringae pv. tomato (Pst); however, this is accomplished primarily via an NPR1-dependent pathway. Analysis of ssi2-1 NPR1 nahG and ssi2-1 npr1-5 nahG plants revealed that elevated SA levels were not essential for the ssi2-1-conferred phenotypes. However, expression of the nahG tran...Continue Reading

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Citations

Mar 29, 2006·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Molly Cadle-Davidson, Molly M Jahn
Mar 13, 2012·Environmental Science and Pollution Research International·Dongwu LiuLina Wang
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Jul 23, 2003·Current Opinion in Plant Biology·Jyoti Shah
Nov 30, 2011·Proceedings of the National Academy of Sciences of the United States of America·Lina Gallego-GiraldoRichard A Dixon
Nov 25, 2011·Molecular Plant-microbe Interactions : MPMI·Ragiba MakandarJyoti Shah
Apr 15, 2005·Molecular Plant-microbe Interactions : MPMI·Ashis NandiJyoti Shah
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