A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function.

Chemical Communications : Chem Comm
Johannes BroichhagenDavid J Hodson

Abstract

Azobenzene photoresponsive elements can be installed on sulfonylureas, yielding optical control over pancreatic beta cell function and insulin release. An obstacle to such photopharmacological approaches remains the use of ultraviolet-blue illumination. Herein, we synthesize and test a novel yellow light-activated sulfonylurea based on a heterocyclic azobenzene bearing a push-pull system.

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Citations

Feb 19, 2016·Chemistry : a European Journal·David B KonradDirk Trauner
Nov 21, 2015·Angewandte Chemie·Johannes BroichhagenDirk Trauner
Sep 20, 2015·Chemistry : a European Journal·Jaume Garcia-AmorósDolores Velasco
Sep 29, 2015·Accounts of Chemical Research·Mingxin DongG Andrew Woolley
Apr 10, 2016·Angewandte Chemie·Johannes BroichhagenDavid J Hodson
Jul 16, 2015·Chemical Communications : Chem Comm·M DongG A Woolley
Jun 24, 2015·Accounts of Chemical Research·Johannes BroichhagenDirk Trauner
May 7, 2016·Journal of the American Chemical Society·Michael M LerchBen L Feringa
Jul 5, 2016·Angewandte Chemie·Michael M LerchBen L Feringa
Aug 20, 2016·Chemical Communications : Chem Comm·Robert J Mart, Rudolf K Allemann
Apr 18, 2018·Journal of Molecular Endocrinology·Daniela Nasteska, David J Hodson
May 4, 2017·Diabetes, Obesity & Metabolism·Guy A RutterIsabelle Leclerc
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Mar 24, 2017·Scientific Reports·Zenobia B MehtaDavid J Hodson
Dec 19, 2017·Physical Chemistry Chemical Physics : PCCP·Jaume Garcia-AmorósDolores Velasco
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Mar 19, 2021·Cell Chemical Biology·Vanessa A GutzeitJohannes Broichhagen
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Feb 22, 2018·Bioconjugate Chemistry·Wan-Chen Lin, Richard H Kramer
Nov 27, 2021·The Journal of Physical Chemistry. B·Katarzyna Walczewska-Szewc, Wieslaw Nowak

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