A reduced protein diet induces stearoyl-CoA desaturase protein expression in pig muscle but not in subcutaneous adipose tissue: relationship with intramuscular lipid formation

The British Journal of Nutrition
O DoranJ D Wood

Abstract

A reduced protein diet (RPD) is known to increase the level of intramuscular lipid in pig meat with a smaller effect on the amount of subcutaneous adipose tissue. This might be due to tissue-specific activation of the expression of lipogenic enzymes by the RPD. The present study investigated the effect of a RPD, containing palm kernel oil, soyabean oil or palm oil on the activity and expression of one of the major lipogenic enzymes, stearoyl-CoA desaturase (SCD) and on the level of total lipids and the fatty acid composition of muscle and subcutaneous adipose tissue in pigs. The RPD significantly increased SCD protein expression and activity in muscle but not in subcutaneous adipose tissue. The level of MUFA and total fatty acids in muscle was also elevated when the RPD was fed, with only small changes in subcutaneous adipose tissue. A positive significant correlation between SCD protein expression and total fatty acids in muscle was found. The results suggest that an increase in intramuscular but not subcutaneous adipose tissue fatty acids under the influence of a RPD is related to tissue-specific activation of SCD expression. It is suggested that the SCD isoform spectra in pig subcutaneous adipose tissue and muscle might be d...Continue Reading

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Citations

Feb 1, 2010·Animal : an International Journal of Animal Bioscience·J F HocquetteD W Pethick
May 1, 2010·Animal : an International Journal of Animal Bioscience·A HerdmannO Doran
Oct 4, 2012·Animal : an International Journal of Animal Bioscience·R BareaJ F Aguilera
Jun 20, 2013·Journal of Animal Science and Biotechnology·Kun LiuLeyan Yan
Oct 1, 2008·International Journal of Biological Sciences·Zhihua JiangMichael D Macneil
Aug 29, 2014·Animal : an International Journal of Animal Bioscience·F SirtoriO Franci
Mar 26, 2013·Gene·Mohammad Reza BakhtiarizadehEsmaeil Ebrahimie
May 30, 2012·Biochemical and Biophysical Research Communications·Ana P MartinsGraça Soveral
Mar 2, 2016·The British Journal of Nutrition·Marta S MadeiraJosé A M Prates
Apr 9, 2010·Meat Science·Verónica AlonsoJosé Antonio Beltrán
Apr 1, 2008·Meat Science·J D WoodF M Whittington
Jan 1, 2013·Meat Science·B RenavilleE Piasentier
Sep 1, 2015·Adipocyte·Gary J HausmanMichael V Dodson
Oct 18, 2016·Animal : an International Journal of Animal Bioscience·P A LopesG Soveral

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