A referral center's experience with transitional cell carcinoma misdiagnosed as interstitial cystitis

The Journal of Urology
William D TissotKenneth M Peters

Abstract

There has been a recent trend to diagnose interstitial cystitis (IC) in a noninvasive way using a potassium sensitivity test, and a pelvic pain, urgency and frequency questionnaire. The concern is that significant pathology causing the bladder symptoms may be missed, such as transitional cell carcinoma. We present our experience with patients "labeled" as having IC who truly had cancer as the cause of irritative symptoms. A retrospective review of patient records at our IC center was performed from 1998 to 2002. A total of 600 patients were seen at that time with the diagnosis of interstitial cystitis. Six patients (1%) previously diagnosed as having IC were found to have transitional cell carcinoma as the cause of symptoms, 4 of whom (67%) had no hematuria. Mean time from the diagnosis of IC to diagnosis of transitional cell carcinoma was 29.8 months. Irritative bladder symptoms resolved after identifying and treating the malignancy. Patients with irritative voiding symptoms require a thorough evaluation which may include cystoscopy, cytology and upper tract imaging. Hematuria was not a good predictor of cancer in our series. In the era before widespread use of minimally invasive means to diagnose IC (ie potassium sensitivity ...Continue Reading

Citations

Aug 17, 2012·International Urogynecology Journal·Joseph KellerHerng-Ching Lin
Nov 16, 2004·Current Urology Reports·Ricardo R Gonzalez, Alexis E Te
Sep 9, 2006·Current Urology Reports·Humphrey O Atiemo, Sandip P Vasavada
Oct 21, 2006·Current Urology Reports·Kenneth M Peters, Donna J Carrico
Aug 16, 2008·Current Urology Reports·Abhishek Seth, Joel M H Teichman
Aug 28, 2009·Current Urology Reports·Frank N Burks, Kenneth M Peters
Jul 26, 2012·Current Urology Reports·Renee B Quillin, Deborah R Erickson
Jul 4, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·G Alessandro DigesuVik Khullar
Apr 5, 2013·International Journal of Impotence Research·S-D ChungH-C Lin
Jan 27, 2009·International Journal of Clinical Practice·J B Forrest, R Moldwin
Jun 15, 2013·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Jin Kyu Oh, Khae-Hawn Kim
Jan 5, 2014·Current Urology Reports·Anthony J Dyer, Christian O Twiss
Mar 28, 2013·Expert Opinion on Medical Diagnostics·Magnus Fall, Ralph Peeker
Apr 2, 2013·The Urologic Clinics of North America·Michael C LargeGary D Steinberg
Apr 28, 2007·Urology·Joel M H Teichman, C Lowell Parsons
Jun 1, 2007·BJU International·Jennifer SouthgateIan Eardley
Mar 15, 2006·Urology·Adrienne J K Carmack, Mark S Soloway
Sep 6, 2005·Urology·Derek P Ottem, Joel M H Teichman
Oct 11, 2017·Female Pelvic Medicine & Reconstructive Surgery·Michael FeloneyNick Dietz
Aug 19, 2008·The Journal of Urology·Rebecca BraunsteinRobert Moldwin
Dec 20, 2011·The Journal of Urology·Kenneth M Peters
Oct 13, 2009·International Journal of Urology : Official Journal of the Japanese Urological Association·Kinue AiharaYoshihiko Hirao
Sep 25, 2012·Neurourology and Urodynamics·Joseph J KellerHerng-Ching Lin
Oct 2, 2012·BJU International·Joseph J KellerHerng-Ching Lin
Jul 25, 2012·Neurourology and Urodynamics·Joseph KellerHerng-Ching Lin
Dec 5, 2008·International Journal of Urology : Official Journal of the Japanese Urological Association·Tomohiro UedaNaoki Yoshimura

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.