Abstract
Hematoma expansion (HE) is an independent predictor of poor outcome and secondary neurological deterioration in intracerebral hemorrhage (ICH) and is associated with high morbidity and mortality. Noncontrast computed tomography (NCCT) may identify the sites of active extravasation. Therefore, we have attempted to (1) devise a reliable and easy-to-use prediction score to predict the risk of HE in ICH and (2) validate the accuracy of this grading system and perform an independent analysis of HE predictors. We included patients in whom an intracerebral hemorrhage (ICH) occurred in the basal ganglia between Jan. 2015 and Jan. 2018. These patients had undergone a baseline CT scan at Qinghai Provincial People's Hospital within 24 hours after the onset of ICH symptoms. Two observers independently assessed the presence of the island sign, blend sign, or swirl sign on an NCCT scan during patient selection. Patients underwent a baseline NCCT scan and 24-hour NCCT follow-up for analysis of HE. The accuracy of this grading system was assessed. Independent predictors of HE were identified using multivariable regression. Of 266 patients with ICH, 61 (22.93%) presented with the island sign, 63 (23.68%) presented with the blend sign, and 50 (1...Continue Reading
References
Oct 12, 2005·Neurology·K ToyodaT Inoue
Apr 26, 2006·Neurology·M L FlahertyD Woo
Feb 10, 2007·Stroke; a Journal of Cerebral Circulation·Joseph P BroderickUNKNOWN Recombinant Activated Factor VII Intracerebral Hemorrhage Trial Investigators
Aug 16, 2008·Stroke; a Journal of Cerebral Circulation·Brett CucchiaraUNKNOWN CHANT Investigators
May 12, 2009·Lancet·Adnan I QureshiDaniel F Hanley
Feb 25, 2011·Neurology·D DowlatshahiUNKNOWN VISTA Collaboration
May 12, 2011·International Journal of Stroke : Official Journal of the International Stroke Society·Dar DowlatshahiUNKNOWN VISTA Collaborators
Jun 21, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Ozlem Kayim YildizMehmet Akif Topcuoglu
Jul 30, 2011·Stroke; a Journal of Cerebral Circulation·David Rodriguez-LunaCarlos A Molina
Aug 10, 2011·Neurosurgery·Joji B KuramatsuHagen B Huttner
Mar 13, 2012·Lancet Neurology·Andrew M DemchukUNKNOWN PREDICT/Sunnybrook ICH CTA study group
Sep 28, 2012·BMC Neurology·Eufrozina SelariuKasim Abul-Kasim
Mar 8, 2013·Cerebrovascular Diseases·H Bart Brouwers, Steven M Greenberg
May 8, 2013·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·D Rodriguez-LunaC A Molina
Sep 12, 2013·Stroke; a Journal of Cerebral Circulation·Javier M RomeroR Gilberto Gonzalez
Dec 25, 2013·JAMA Neurology·H Bart BrouwersJoshua N Goldstein
Dec 17, 2014·Stroke; a Journal of Cerebral Circulation·Xia WangUNKNOWN INTERACT Investigators
May 13, 2015·Neurocritical Care·Xiaoying YaoMagdy Selim
Jun 20, 2015·Stroke; a Journal of Cerebral Circulation·Qi LiPeng Xie
Oct 16, 2015·Stroke; a Journal of Cerebral Circulation·Thien J HuynhUNKNOWN PREDICT/Sunnybrook CTA Investigators
Oct 12, 2017·Stroke; a Journal of Cerebral Circulation·Qi LiPeng Xie
Nov 7, 2017·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Masaaki HokariKoji Itamoto
Jan 10, 2018·Bioscience Trends·Ruili Li, Mingfei Yang
Citations
Jan 23, 2020·Stroke; a Journal of Cerebral Circulation·Vignan YogendrakumarDar Dowlatshahi
Aug 9, 2020·Frontiers in Neurology·Zhifang LiBo Hu
Jun 26, 2020·Frontiers in Neurology·Yufei WeiYing Gao
Mar 13, 2021·Current Neurology and Neuroscience Reports·Xin-Ni LvQi Li
Nov 19, 2019·Medicina intensiva·X Y KongZ Y Qian
Apr 18, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Michael AmooMohammed Ben Husien
Apr 27, 2021·Human & Experimental Toxicology·L WuW Chen