PMID: 20103819Jan 28, 2010Paper

A retroperitoneal mass with elevated alpha-1-fetoprotein: not always a testicular carcinoma

The Netherlands Journal of Medicine
F Toonen, T Smilde

Abstract

High levels of alpha-1-fetoprotein are usually associated with nonseminoma carcinoma of the testis or hepatocellular carcinoma of the liver. We describe a male patient with extrahepatic hepatocellular carcinoma who presented with a large retroperitoneal mass and extremely high alpha-1-fetoprotein levels. The importance of taking an adequate biopsy specimen cannot be emphasised enough since both prognosis and treatment are completely different.

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