A Retrospective Analysis of Cyanoacrylate Injection versus Hemoclip Placement for Bleeding Dieulafoy's Lesion in Duodenum

Gastroenterology Research and Practice
Yu JiangHongshan Wei

Abstract

Duodenal Dieulafoy's lesion (DL) is a rare disease that may lead to lethal hemorrhage in the upper gastrointestinal tract. The best technique for endoscopic intervention still remains unclear. In the present study, we performed a retrospective analysis of cyanoacrylate injection versus hemoclip placement for treating bleeding DLs. We retrospectively analyzed eighteen patients from three medical centers between October 2008 and February 2016; six patients received cyanoacrylate injection, while hemoclips were placed in 12 patients during the upper gastrointestinal endoscopy. All patients received first endoscopic examination and/or endotherapy within 12 hours of admission to hospital. No difference was observed in the primary hemostasis rate or the recurrent hemorrhage rate between the cyanoacrylate injection (CI) group and the hemoclip placement (HP) group, except that in one patient from the HP group melena was found three days after the first endotherapy. This patient received cyanoacrylate injection once again. Both cyanoacrylate injection and hemoclip placement are effective in treating duodenal DL, and neither of them causes significant side effects.

References

Jan 1, 1978·AJR. American Journal of Roentgenology·A LunderquistS Bengmark
Sep 1, 1992·Gastrointestinal Endoscopy·M E StarkR K Balm
Feb 1, 1988·The Tohoku Journal of Experimental Medicine·S AsakiN Yaginuma
Dec 1, 1994·Digestive Diseases and Sciences·D JaspersenC H Hammar
Mar 7, 1998·Scandinavian Journal of Gastroenterology·L B NesjeS Odegaard
Apr 14, 1999·The American Journal of Gastroenterology·K McGrathS Branch
Mar 30, 2002·Gastrointestinal Endoscopy·Panagiotis KasapidisNikolaos Skandalis
Mar 19, 2003·Journal of Clinical Gastroenterology·Rushda MumtazFrancisco C Ramirez
Apr 24, 2003·Gastrointestinal Endoscopy·Yasuharu YamaguchiShin-ichi Takahashi
Sep 25, 2004·Digestive Diseases and Sciences·Chi-Liang ChengCheng-Tang Chiu
Nov 8, 2005·World Journal of Gastroenterology : WJG·Panagiotis KatsinelosYiannis Kountouras
Sep 1, 2008·Therapeutic Advances in Gastroenterology·Gustavo López-ArceFélix I Téllez-Ávila
Nov 17, 2012·World Journal of Gastroenterology : WJG·Yuliana Jamanca-PomaAntonio Rodríguez-Pérez
May 3, 2014·Digestive Diseases and Sciences·Arslan KahloonMichael Chiorean
Feb 11, 2015·Digestive Diseases and Sciences·Rajan KanthPraveen K Roy
Apr 7, 2015·Clinical Endoscopy·Hye Kyung Jeon, Gwang Ha Kim
Jun 2, 2016·Journal of Gastroenterology·Hiroshi FukuiTooru Shimosegawa
Aug 31, 2016·World Journal of Gastrointestinal Pathophysiology·Anjana SathyamurthyVeysel Tahan

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Citations

Sep 11, 2020·Canadian Journal of Gastroenterology & Hepatology·Yongkang LaiXu Shu
Aug 11, 2020·GE Portuguese Journal of Gastroenterology·Paulo MassinhaLuís Tomé

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