A retrospective analysis of distinguishing features of chest HRCT and clinical manifestation in primary Sjögren's syndrome-related interstitial lung disease in a Chinese population

Clinical Rheumatology
Xin DongYi Zheng

Abstract

To characterize the distinctive chest high-resolution computerized tomography (HRCT) features and clinical manifestations of primary Sjögren syndrome (pSS)-related interstitial lung disease (ILD). The demographic data, clinical manifestations, and laboratory and radiological findings of 527 pSS patients were retrospectively analyzed. ILD was defined based on the presences of pulmonary signs in HRCT. Two hundred six of 527 patients were diagnosed as pSS-ILD, and the prevalence was 39.1%. The three most frequent abnormalities in HRCT were reticular pattern (92.7%), ground-glass attenuation (87.4%), and bronchovascular bundle thickening (82%). One hundred twenty-four cases (60.2%) of the pSS-ILD patients had only a single HRCT pattern, which involved 86 non-specific interstitial pneumonitis (NSIP) cases (41.7%), 22 usual interstitial pneumonia (UIP) cases (10.68%), 8 organizing pneumonia (OP) cases (3.9%), and 8 lymphocytic interstitial pneumonia (LIP) cases (3.9%), respectively. Besides, the more important observation was that 82 cases had no less than two HRCT patterns, and NSIP admixed with OP (43.9%), NSIP admixed with UIP (35.4%), and NSIP admixed with LIP (19.5%) were the most frequent. HRCT of pSS-ILD patients demonstrated ...Continue Reading

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Citations

Mar 15, 2019·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Patricia Jordán-GonzálezLuis M Vilá
Nov 9, 2019·PloS One·Pablo Guisado-VascoAlarico Ariani
Aug 9, 2020·Frontiers in Medicine·Georgios SogkasDiana Ernst
Oct 11, 2020·BMC Pulmonary Medicine·Shunsuke UnoUNKNOWN Nontuberculous Mycobacteriosis and Bronchiectasis-Japan Research Consortium (NTM-JRC)
May 12, 2021·European Journal of Internal Medicine·Paul DeckerRoland Jaussaud
Jul 27, 2021·International Journal of Clinical Practice·Tugce Sahin OzdemirelYurdanur Erdogan
Sep 3, 2021·Therapeutic Advances in Musculoskeletal Disease·Panagiotis PanagopoulosAthanasios Tzioufas
Nov 12, 2019·Respiratory Medicine·Yosuke KamiyaTakafumi Suda

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