A Retrospective Database Study Comparing Diabetes-Related Medication Adherence and Health Outcomes for Mail-Order Versus Community Pharmacy

Journal of Managed Care & Specialty Pharmacy
Phil SchwabKaren Worley

Abstract

Adherence to oral antihyperglycemic agents (AHAs) is important for managing blood glucose levels and avoiding hospitalizations or diabetes complications. Previous studies have found that use of mail-order pharmacy dispensing channels results in greater adherence than use of community pharmacies, but the link between use of mail-order pharmacies and improved clinical outcomes has not been established. To compare the effect of mail-order and community pharmacy use on adherence to oral AHAs, hemoglobin A1c (A1c) level, and glycemic control, as well as emergency department (ED) and inpatient hospital use. This retrospective cohort study of administrative claims data from January 1, 2008, to December 31, 2016, included patients with Medicare Advantage Prescription Drug plan coverage with ≥ 2 claims for the same oral AHA and a diagnosis of type 2 diabetes mellitus (T2DM). Patients were indexed to the start of the most advanced oral AHA identified to begin study observations at the start of a new treatment and assigned to mail-order or community pharmacy cohorts based on which channel dispensed ≥ 80% of their oral AHA claims; all others were excluded. Mail-order and community pharmacy patients were 1:1 propensity score matched. Matche...Continue Reading

References

Jan 9, 2001·Journal of Clinical Epidemiology·C N KlabundeJ L Warren
Jan 25, 2003·Medical Care·Paul A FishmanMaureen C O'Keeffe Rosetti
May 24, 2005·Medical Care·Michael C SokolRobert S Epstein
Jun 29, 2005·American Journal of Public Health·L Gary HartDenise M Lishner
Jul 25, 2006·Medical Care·Michael L JohnsonNeena S Abraham
May 6, 2009·Australian and New Zealand Journal of Public Health·Agnes VitryJohn Barratt
Dec 22, 2010·Journal of Clinical Epidemiology·Christine Y LuElizabeth Roughead
Jul 7, 2011·Journal of Medical Economics·Lihua ZhangBrian K Solow
Feb 23, 2012·Medical Care·Krishna P Sharma, Thomas N Taylor
Jan 1, 2012·Medicare & Medicaid Research Review·Michael TaitelIan Duncan
Dec 10, 2017·Diabetes Care·UNKNOWN American Diabetes Association

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Citations

May 29, 2019·Journal of Managed Care & Specialty Pharmacy
May 29, 2019·Journal of Managed Care & Specialty Pharmacy
Mar 3, 2020·The Annals of Pharmacotherapy·Natalia Shcherbakova, Shane Desselle
Oct 2, 2020·Journal of General Internal Medicine·Bharathi RamachandranJulie A Schmittdiel

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