A Retrospective Dosimetric Analysis of the New ESTRO-ACROP Target Volume Delineation Guidelines for Postmastectomy Volumetric Modulated Arc Therapy After Implant-Based Immediate Breast Reconstruction

Frontiers in Oncology
Kyung Hwan ChangChae-Seon Hong

Abstract

Purpose: The European Society of Radiation & Oncology and Advisory Committee on Radiation Oncology Practice (ESTRO-ACROP) presented new guidelines for clinical target volume (CTV) delineation in post-mastectomy radiation therapy (PMRT) after implant-based immediate breast reconstruction (IBR-i). This study evaluated the dosimetric characteristics, dosimetric accuracy, and delivery accuracy of these guidelines in volumetric modulated arc therapy (VMAT). Methods and Materials: This retrospective study included 15 patients with left breast cancer who underwent mastectomy with tissue expander placement followed by PMRT. An experienced radiation oncologist delineated the CTV twice on the same image datasets based on the ESTRO-ACROP (EA-TVD) and conventional target volume delineation (C-TVD) guidelines. All VMAT plans, which used a double partial arc, were generated using six MV photons. Clinically relevant dose-volume parameters for organs at risk were compared. Dosimetric accuracy of the treatment plans and delivery accuracy were assessed. Results: Target volume of EA-TVD was significantly smaller than that of C-TVD. Although no statistically significant difference was noted in the target coverage between the two VMAT plans, EA-TVD...Continue Reading

References

Dec 1, 1993·International Journal of Radiation Oncology, Biology, Physics·E ShawL Martin
Jun 13, 2006·International Journal of Radiation Oncology, Biology, Physics·Sabin B MotwaniThomas A Buchholz
Jun 17, 2008·International Journal of Radiation Oncology, Biology, Physics·Marilyn StovallUNKNOWN Women's Environmental, Cancer, and Radiation Epidemiology Study Collaborative Group
Aug 24, 2011·Medical Physics·Nicolini GiorgiaCozzi Luca
Mar 15, 2013·The New England Journal of Medicine·Sarah C DarbyPer Hall
Jan 22, 2014·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Yasser Abo-MadyanGerhard Glatting
Feb 20, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Reshma JagsiBenjamin D Smith
Jan 30, 2015·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Birgitte V OffersenPhilip Poortmans
Jul 15, 2015·Radiation Oncology·Tanja SkyttäPirkko-Liisa Kellokumpu-Lehtinen
Jan 18, 2017·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Veerle A B van den BogaardAnne P G Crijns
Jun 25, 2017·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Mazen SakkaGerhard G Grabenbauer
Jul 26, 2017·Plastic and Reconstructive Surgery. Global Open·Orit Kaidar-PersonTimothy M Zagar
Sep 17, 2017·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Stefanie CorradiniClaus Belka
Oct 8, 2017·The Journal of Surgical Research·Joseph A RicciBernard T Lee
Dec 7, 2017·The Lancet Oncology·Alice Y HoEdwin G Wilkins
Jan 10, 2018·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Mar 30, 2018·Plastic and Reconstructive Surgery·Clifford C SheckterEvan Matros
May 29, 2018·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·LiCheng KuoLinda Hong
Aug 14, 2018·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J FerlayF Bray
May 21, 2019·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Orit Kaidar-PersonPhilip Poortmans
Aug 28, 2019·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Orit Kaidar-PersonPhilip Poortmans
Aug 28, 2019·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Robert W Mutter

❮ Previous
Next ❯

Citations

Jun 9, 2021·Critical Reviews in Oncology/hematology·Hannah M DahnOrit Kaidar-Person

❮ Previous
Next ❯

Methods Mentioned

BETA
dissection

Software Mentioned

MIM
ACROP
RayStation
SNC Patient
ESTRO
RayStation system TPS
SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.