A retrospective study of dermatitis herpetiformis from an immunobullous disease clinic in north India

International Journal of Dermatology
Sanjeev HandaBishan Das Radotra

Abstract

Indian data on dermatitis herpetiformis (DH) is not available. The aim of this study was to investigate the demographic and clinicopathological characteristics of patients with DH and to study its association with other autoimmune diseases. All data were collected from case record forms of patients registered in immunobullous disease clinic of our institute. The diagnosis was based on characteristic clinical and immuno/histopathological features. A total of 65 patients were included, which constituted 9.47% of the registered patients in the immunobullous disease clinic over 3.5 years. The male to female ratio was 1.4 : 1; the average age was 44.35 ± 15.52 years. Direct immunofluorescence showed granular IgA deposits at the papillary tips in 83.07% and basement membrane zone in 12.3% patients. Sixteen (24.1%) patients had associated celiac disease, and 15 (23.07%) patients had other autoimmune comorbidities such as hypothyroidism. Forty percent of patients on strict gluten-free diet achieved remission in 2 years, while 35.4% had frequent relapses as they continued gluten intake. Dermatitis herpetiformis is not a rare disease in northern India as previously believed. The clinical, histological, and immunopathological characterist...Continue Reading

References

Nov 1, 1977·The British Journal of Dermatology·T ReunalaK Kangas
Feb 9, 2002·Dermatology : International Journal for Clinical and Investigative Dermatology·M ShibaharaH Shimizu
Dec 13, 2002·American Journal of Clinical Dermatology·Pekka Collin, Timo Reunala
Apr 13, 2005·Gastroenterology·John J Zone
Sep 8, 2007·International Journal of Dermatology·Javier Alonso-LlamazaresRoy S Rogers
May 28, 2009·Journal of the European Academy of Dermatology and Venereology : JEADV·M CaproniUNKNOWN Italian Group for Cutaneous Immunopathology
Dec 25, 2010·Journal of Gastroenterology and Hepatology·Govind K MakhariaKrishnan Anand
Oct 29, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·F ZhangD Zhang
Dec 23, 2015·Indian Journal of Endocrinology and Metabolism·Sadishkumar KamalanathanMuthupillai Vivekanandan
Apr 19, 2016·Indian Journal of Dermatology, Venereology and Leprology·Dipankar DeRanjana W Minz

❮ Previous
Next ❯

Citations

Jan 13, 2021·American Journal of Clinical Dermatology·Timo ReunalaTeea Salmi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Clinical, Cosmetic and Investigational Dermatology
Emiliano Antiga, Marzia Caproni
Dermatology : International Journal for Clinical and Investigative Dermatology
M ShibaharaH Shimizu
Annales de dermatologie et de vénéréologie
S Ingen-Housz-Oro
© 2022 Meta ULC. All rights reserved