PMID: 16529017Mar 15, 2006Paper

A retrospective study of malignant parotid tumors

Nihon Jibiinkoka Gakkai kaiho
Kikuo SakamotoTadashi Nakashima

Abstract

The clinical features of 74 patients (39 men, 35 women; mean age, 62 years) with malignant parotid tumors were retrospectively investigated. According to the TNM Classification, 4 patients were classified as T1, 9 as T2, 6 as T3, and 55 as T4. Fifty cases were staged as N0, 9 as N1, 14 as N2 and 1 as N3. Tumors located in both lobes of the parotid gland were the most frequent type of tumor (49%). Twenty-four percent of the 74 patients exhibited facial nerve palsy before treatment. Facial palsy was found predominantly in cases with a higher T classification or with deep lobe occupation. Histopathologically, sixteen tumor types were observed; mucoepidermoid carcinoma was the most common. The overall five-year and ten-year survival rates determined using the Kaplan-Meier method were 65% and 61%. The factors influencing a poor outcome were T4 classification (p=0.0189), an N+ stage (p<0.0001), and facial palsy (p<0.0001). As for the major histopathologic types, the five-year survival rates were 69% for mucoepidermoid carcinoma, 48% for adenocarcinoma, 71% for adenoid cystic carcinoma, and 100% for acinic cell carcinoma and malignant mixed tumor. With respect to the treatment modality, patients who were classified as T1 or T2 and who...Continue Reading

Citations

Apr 15, 2010·Nihon Jibiinkoka Gakkai kaiho·Yoshifumi FujitaMamoru Tsukuda
Jan 13, 2010·Hematology/oncology and Stem Cell Therapy·Nabil Al-ZaherBassam Sulaiman Al-Kayyali

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