PMID: 6160600Jan 1, 1980Paper

A review of clinical studies of pepleomycin

Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer
S Oka

Abstract

Pulmonary toxicity was less frequent in pepleomycin treatment of squamous cell carcinoma than in bleomycin treatment. The tumor-regressing effect appeared at about day 10 of pepleomycin treatment, and at about day 21 of bleomycin treatment. The cumulative dose of pepleomycin to complete remission was smaller than that of bleomycin. Pepleomycin is effective against bleomycin-sensitive malignancies: squamous cell carcinoma and Hodgkin's disease. It is more effective than bleomycin against lymph node metastases. Pepleomycin may have a broader antitumor spectrum: prostatic carcinoma responded.

Citations

Nov 20, 2016·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Teresa E LehmannMark H Harpster
Feb 18, 2011·The Journal of Antibiotics·Teresa E LehmannGeoffrey S Armstrong
Jul 28, 2017·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Shelby E FollettTeresa E Lehmann
Aug 7, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Teresa Lehmann, Elena Topchiy
Apr 10, 2012·Journal of Inorganic Biochemistry·Yang Li, Teresa Lehmann
Jan 1, 1991·The International Journal of Biochemistry·B ZhangS Ikeda

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