A review of empirical evidence of somatic treatment options for the MI/DD population.

The Psychiatric Quarterly
Thaddeus P Ulzen, Richard E Powers

Abstract

This article reviews recent evidence in the literature for the use of psychotropic and other somatic treatments in the management of patients with mental retardation (MR). The search methodology included peer-reviewed English language publications in PubMed and PsychINFO with the words Mental Retardation, Intellectual Disability, Developmental Disability and Mental Disorders/Drug Therapy or Antipsychotic medications, Psychiatric Somatic therapies, Neuroleptic Drugs, Antidepressants and Electroconvulsive Therapy from 1998 to 2008. The review revealed few randomized controlled trials on the medications frequently prescribed for patients with MR. Three RCTs of Risperidone in children, one combining adults and children and one with adults only are discussed. There was one RCT involving Quetiapine and one on Citalopram. There is little evidence to support the scope of psychotropic medication use in the MR population though the field is advancing. The contribution of psychiatric illness to challenging behaviors is not systematically addressed in the literature.

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Citations

Apr 18, 2015·Journal of Applied Research in Intellectual Disabilities : JARID·Arlette ScheifesEibert R Heerdink
Apr 1, 2015·Journal of Applied Research in Intellectual Disabilities : JARID·Janet RobertsonEric Emerson
May 21, 2016·The British Journal of Psychiatry : the Journal of Mental Science·Nadine KoslowskiBernd Puschner
Mar 16, 2013·Psychiatric Genetics·Stefano VicariMarco Armando

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