A review of health utilities using the EQ-5D in studies of cardiovascular disease.

Health and Quality of Life Outcomes
Matthew T D DyerMartin J Buxton

Abstract

The EQ-5D has been extensively used to assess patient utility in trials of new treatments within the cardiovascular field. The aims of this study were to review evidence of the validity and reliability of the EQ-5D, and to summarise utility scores based on the use of the EQ-5D in clinical trials and in studies of patients with cardiovascular disease. A structured literature search was conducted using keywords related to cardiovascular disease and EQ-5D. Original research studies of patients with cardiovascular disease that reported EQ-5D results and its measurement properties were included. Of 147 identified papers, 66 met the selection criteria, with 10 studies reporting evidence on validity or reliability and 60 reporting EQ-5D responses (VAS or self-classification). Mean EQ-5D index-based scores ranged from 0.24 (SD 0.39) to 0.90 (SD 0.16), while VAS scores ranged from 37 (SD 21) to 89 (no SD reported). Stratification of EQ-5D index scores by disease severity revealed that scores decreased from a mean of 0.78 (SD 0.18) to 0.51 (SD 0.21) for mild to severe disease in heart failure patients and from 0.80 (SD 0.05) to 0.45 (SD 0.22) for mild to severe disease in angina patients. The published evidence generally supports the val...Continue Reading

Associated Clinical Trials

Jan 30, 2017·Albert Marni Joensen

References

Oct 1, 1993·Journal of the American College of Cardiology·G H Guyatt
Aug 1, 1997·Cardiovascular Surgery : Official Journal of the International Society for Cardiovascular Surgery·T A Cook, R B Galland
Nov 21, 1997·Medical Care·P Dolan
Sep 22, 1998·Annals of Surgery·J A SollanoR J Greene
Jun 8, 2000·Medical Care·T O Tengs, A Wallace
Jul 6, 2000·Journal of Psychosomatic Research·J R Swenson, J J Clinch
Aug 9, 2001·Annals of Medicine·R Rabin, F de Charro
Apr 10, 2002·Journal of Health Economics·John BrazierMark Deverill
Jun 8, 2002·Stroke; a Journal of Cerebral Circulation·David SulchLalit Kalra
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Sep 26, 2002·Resuscitation·Cristina GranjaAltamiro Costa-Pereira
Apr 19, 2003·Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy·Camilla HageAgneta Ståhle
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Sep 6, 2003·Cardiovascular Surgery : Official Journal of the International Society for Cardiovascular Surgery·M A MaliwaF E E Vermeulen
Jan 10, 2004·Health and Quality of Life Outcomes·Stefan HöferNeil Oldridge
Mar 3, 2004·Circulation·Victor M G LegrandUNKNOWN Arterial Revascularization Therapy Study (ARTS) Investigators
Apr 17, 2004·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·N J A van ExelM A Koopmanschap
Jun 4, 2004·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Patricia E M LottmanJacob Buth
Sep 8, 2004·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·E Anne LaceyPeter Scott
Dec 3, 2004·ANZ Journal of Surgery·Carole A SpencerMichael Lawrence-Brown
Dec 21, 2004·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Wolfgang GreinerFrank de Charro
Feb 3, 2005·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Fiona M ShriveUNKNOWN APPROACH Investigators
Mar 9, 2005·The New England Journal of Medicine·John G F ClelandUNKNOWN Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators
Mar 26, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·David NowelsSherry Holcomb
Mar 26, 2005·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·A Simon PickardDavid H Feeny
Jun 23, 2005·Medical Care·Patrick W SullivanVahram Ghushchyan
Jul 6, 2005·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M J AriesenUNKNOWN Dutch Bypass Oral Anticoagulants or Aspirin Study Group
Sep 30, 2005·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Louise LongworthDavid H Smith
Oct 8, 2005·American Heart Journal·John SpertusUNKNOWN Cardiovascular Outcomes Research Consortium
Dec 13, 2005·Stroke; a Journal of Cerebral Circulation·Caroline HaackeRichard Dodel
Feb 24, 2006·European Heart Journal·José LealMike Rayner
Mar 15, 2006·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Mattie LenzenWilliam Wijns
Mar 28, 2006·Health and Quality of Life Outcomes·Henk F van Stel, Erik Buskens
May 18, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·I C van der SchaafG J E Rinkel

❮ Previous
Next ❯

Citations

Jan 11, 2012·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Karl WerdanUrsula Müller-Werdan
Mar 12, 2013·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Ulrike TheidelHugo Katus
Oct 24, 2012·Health Care Management Science·George MillerCharles Roehrig
Oct 24, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Weena Saiguay, Phantipa Sakthong
Nov 28, 2012·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M F JanssenJan Busschbach
Jun 12, 2012·BMC Health Services Research·Raj S PadwalArya M Sharma
May 9, 2014·German Medical Science : GMS E-journal·Karl-Heinz LadwigChristoph Herrmann-Lingen
Feb 5, 2013·Journal of Occupational Rehabilitation·M F RenemanR Escorpizo
May 23, 2014·PharmacoEconomics·Ayse Kuspinar, Nancy E Mayo
Feb 10, 2016·Pacing and Clinical Electrophysiology : PACE·Jennifer L MillerDebra K Moser
Apr 14, 2016·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Kathleen L GradyJames K Kirklin
Dec 3, 2014·International Journal of Cardiology·Silke ApersUNKNOWN International Society for Adult Congenital Heart Disease (ISACHD)
Feb 24, 2015·JACC. Cardiovascular Interventions·Ruben L OsnabruggeUNKNOWN CoreValve U.S. Trial Investigators
Jan 1, 2015·European Heart Journal. Cardiovascular Pharmacotherapy·Ariel Dogliotti, Robert P Giugliano
Sep 20, 2011·Heart Failure Clinics·Shelby D ReedKevin A Schulman
May 29, 2013·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Krishna Kumar, Syed Rizvi
Sep 10, 2015·Infectious Diseases and Therapy·Mark MullikinEckhardt Petri
Dec 22, 2015·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Michael LaxyRolf Holle
May 8, 2013·European Journal of Heart Failure·Imke H KraaiHans L Hillege
Aug 17, 2011·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Marcus Eng Hock OngMuhammad Naeem Khan
Jun 28, 2014·Evidence-based Complementary and Alternative Medicine : ECAM·Huan-Lin WuXin-Min Ruan
Dec 24, 2013·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Kathleen L GradyJames Young
Jul 28, 2015·Journal of Vascular Surgery·Ahmed KayssiLouis L Nguyen
Apr 22, 2015·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Janine BiermannTill Neumann
Jul 15, 2015·Journal of Cardiac Failure·Carolyn Miller ReillySandra B Dunbar
Jul 4, 2012·International Journal of Cardiology·Delphine De SmedtUNKNOWN EUROASPIRE Study Group
Apr 29, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Veronica BonaMartyn Thomas
Feb 1, 2015·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Noelle E CarlozziJane S Paulsen

❮ Previous
Next ❯

Methods Mentioned

BETA
amputation

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.