A review of new developments in tissue engineering therapy for periodontitis

Dental Clinics of North America
Taka Nakahara

Abstract

This article focuses on recent advances in the regeneration of periodontium using tissue engineering and examines new technologies that will lead to further advances in periodontal therapy. The various advantages and drawbacks of protein-based, cell-based, and genetic-engineering approaches are evaluated. The debate between those who aim to regenerate periodontal tissues and researchers who have focused on the reconstitution of structural elements of the teeth is examined. The isolation of human dental stem cells from deciduous and adult wisdom teeth might hold the key to allowing the replacement of teeth and the regeneration of supporting tissue. The combination of scientific research, following on from advances in other fields, with clinical research in dentistry could yield a solution to the debilitating and widespread problem of periodontitis.

References

Apr 2, 1999·Science·M F PittengerD R Marshak
Jun 6, 2000·Advanced Drug Delivery Reviews·Y Ikada, Y Tabata
Feb 13, 2001·Annual Review of Medicine·U A Stock, J P Vacanti
Sep 26, 2002·Journal of Periodontology·Knut A SelvigUlf M E Wikesjö
Apr 2, 2003·Journal of Periodontology·Q M JinW V Giannobile
Apr 30, 2003·Proceedings of the National Academy of Sciences of the United States of America·Masako MiuraSongtao Shi
Aug 5, 2003·Biomaterials·Enrico LucarelliPiero Picci
Aug 9, 2003·The New England Journal of Medicine·Martin Kørbling, Zeev Estrov
Oct 2, 2003·Nature Biotechnology·Shuguang Zhang
Nov 1, 2003·Nature Materials·G Bao, S Suresh
Jan 16, 2004·Gene Therapy·Y GafniD Gazit
Feb 26, 2004·Journal of Dental Research·W L MurphyD J Mooney
Apr 20, 2004·Molecular Therapy : the Journal of the American Society of Gene Therapy·Qiming JinWilliam V Giannobile
Jun 26, 2004·Journal of Dental Research·A OhazamaP T Sharpe
Jun 26, 2004·Journal of Dental Research·M T DuailibiP C Yelick
Jul 13, 2004·Trends in Biotechnology·Dietmar W HutmacherMakarand V Risbud
Aug 7, 2004·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Vera LuginbuehlBruno Gander
Oct 7, 2004·Current Opinion in Biotechnology·Christian JorgensenDanielle Noel
Oct 29, 2004·Gene Therapy·P C EdwardsJ M Mason
Nov 2, 2004·Journal of Periodontology·Hiroyuki KawaguchiHidemi Kurihara
Nov 16, 2004·Trends in Biotechnology·Wai-Yee YeongMargam Chandrasekaran
Dec 23, 2004·Journal of Periodontal Research·Kuo-Kuang HuangEarl Fu
Dec 23, 2004·Surgery·Shyh-Jou Shieh, Joseph P Vacanti
Apr 21, 2005·Journal of Dental Research·J-P FréchetteG Gagnon
Apr 28, 2005·Journal of Periodontal Research·Tatsuya AkizukiIsao Ishikawa
Jun 2, 2005·Biotechnology and Bioengineering·Mohamed N Rahaman, Jeremy J Mao
Jul 14, 2005·Biomaterials·Joseph YangTeruo Okano
Jul 19, 2005·Orthodontics & Craniofacial Research·S ShiS Gronthos

❮ Previous
Next ❯

Citations

Feb 26, 2013·In Vitro Cellular & Developmental Biology. Animal·Masanori NasuHiroshi Ishikawa
Jun 19, 2008·Tissue Engineering. Part a·Morikuni TobitaHiroshi Mizuno
Oct 29, 2009·Tissue Engineering. Part B, Reviews·Fa-Ming Chen, Yan Jin
Jan 18, 2011·The Journal of Craniofacial Surgery·Dmitry BulginDanijela Komljenovic-Blitva
Nov 17, 2007·Artificial Organs·Bülend InançY Murat Elçin
May 30, 2013·Indian Journal of Human Genetics·Shalu RaiSapna Panjwani Arora
May 21, 2008·Journal of Biomedical Materials Research. Part a·Bülend InançY Murat Elçin
Nov 3, 2009·Periodontology 2000·Isao IshikawaTomohiro Ando
Jun 12, 2013·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Yoshiaki IdeYuichi Tamaki
Mar 11, 2016·Journal of Periodontology·Bruna R AmorimFrancisco H Nociti
May 23, 2012·Journal of Microencapsulation·Zeliha SoranMenemşe Gümüşderelioğlu
May 18, 2012·Dental Materials : Official Publication of the Academy of Dental Materials·Marco C BottinoGregg M Janowski
Sep 15, 2011·The Open Dentistry Journal·Nesrine Z MostafaTarek H El-Bialy
Aug 29, 2020·Annals of Maxillofacial Surgery·Mehvish SaleemSoundarya Singh

❮ Previous
Next ❯

Related Concepts

Related Feeds

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.