A review of non-invasive imaging in extramammary Paget's disease

Journal of the European Academy of Dermatology and Venereology : JEADV
C-A Y BayanN C Zeitouni

Abstract

Extramammary Paget's Disease (EMPD) is a rare intraepithelial adenocarcinoma that classically manifests with pruritic, erythematous and scaling plaques. The clinical picture frequently mimics inflammatory or infectious conditions and is thus commonly misdiagnosed. The assessment of tumour margins is equally challenging as tumours have a propensity to spread beyond clinically visible boundaries. Appropriate non-invasive diagnostic tools can assist in the early detection, diagnosis and management of EMPD. This paper will review the literature on non-invasive imaging modalities used in EMPD. Articles from the PubMed database were selected based on relevance to the topic of this review. Articles that were not specific to EMPD and non-invasive imaging were excluded. Search strategy is further described in the methods section below. Eighteen articles were selected for this review: six PET/CT, five reflectance confocal microscopy (RCM), two photodynamic diagnosis (PDD), two dermoscopy, two MRI and one optical coherence tomography (OCT) paper(s). Dermoscopy, PDD, RCM and OCT can help to distinguish malignant conditions, including EMPD, from benign conditions. RCM and OCT can identify atypical cells in real-time, and have the potential ...Continue Reading

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Citations

Feb 21, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·Z KangM Guan
Aug 9, 2020·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Jen-Yu WangYu-Hung Wu
Sep 27, 2019·BJR Case Reports·Young Sup ShimHee Joo Kim
May 31, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Si-Tong ChenHui-Xiong Xu
Sep 27, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·A Rajabi-EstarabadiK Nouri
Feb 25, 2021·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Cristian Navarrete-DechentAnthony M Rossi
Apr 16, 2021·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yuan-Yuan MaLe-Hang Guo

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