A Review of Options for Localization of Axillary Lymph Nodes in the Treatment of Invasive Breast Cancer

Academic Radiology
Ryan W WoodsSusan C Harvey

Abstract

Invasive breast cancer is a common disease, and the most common initial site of metastatic disease are the axillary lymph nodes. As the standard of care shifts towards less invasive surgery in the axilla for patients with invasive breast cancer, techniques have been developed for axillary node localization that allow targeted dissection of specific lymph nodes without requiring full axillary lymph node dissection. Many of these techniques have been adapted from technologies developed for localization of lesions within the breast and include marker clip placement with intraoperative ultrasound, carbon-suspension liquids, localization wires, radioactive seeds, magnetic seeds, radar reflectors, and radiofrequency identification devices.The purpose of this article is to summarize these methods and describe benefits and drawbacks of each method for performing localization of lymph nodes in the axilla.

Citations

Jul 16, 2019·Breast Cancer Research and Treatment·Caroline McGuginMichelle Specht
Dec 14, 2019·Current Opinion in Obstetrics & Gynecology·Nina DitschThorsten Kuehn
May 5, 2020·Journal of Clinical Imaging Science·Christine LeeNicholas Hangiandreou
Apr 22, 2020·Radiology·Jung Min ChangWoo Kyung Moon
Jul 26, 2019·Annals of Surgical Oncology·Jennifer M Racz, Abigail S Caudle
Jan 20, 2021·Ultrasound Quarterly·Davis C TeichgraeberGary J Whitman
Oct 7, 2021·AJR. American Journal of Roentgenology·Mary S GuirguisGary J Whitman

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