A review of studies of the effect of severe malnutrition on mental development

The Journal of Nutrition
S Grantham-McGregor

Abstract

This is a review of studies on the relationship between mental development and severe malnutrition. School-age children who suffered from early childhood malnutrition have generally been found to have poorer IQ levels, cognitive function, school achievement and greater behavioral problems than matched controls and, to a lesser extent, siblings. The disadvantages last at least until adolescence. There is no consistent evidence of a specific cognitive deficit. The evidence of a causal relationship is strong but not unequivocal because of difficulties in interpreting retrospective case control studies. Marked improvements in development can occur after adoption or intervention. Therefore, the outcome depends to a large extent on the quality of the subsequent environment. It is likely that extremely deprived environments would exacerbate the effects. There is limited evidence that other nutritional deficiencies may interact with previous malnutrition in affecting cognition. The mechanism linking malnutrition to poor development is still not established.

Citations

Mar 1, 1997·The Proceedings of the Nutrition Society·S P Walker
Jan 29, 2000·The American Journal of Clinical Nutrition·J L HautvastL A Monnens
Feb 3, 2005·European Journal of Clinical Nutrition·K E WebbD L Katz
Sep 6, 2006·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Debbie S GipsonMaria E Ferris
Sep 22, 2006·The Journal of Nutrition·Jena D HamadaniSally M Grantham-McGregor
Jan 30, 2008·Basic & Clinical Pharmacology & Toxicology·Gail A WassermanJoseph H Graziano
Feb 3, 2011·Journal of Developmental and Behavioral Pediatrics : JDBP·Deborah P WaberJanina R Galler
Sep 14, 2011·Developmental Neuroscience·Francisco Romero CabralMaria da Graça Naffah-Mazzacoratti
Apr 21, 2012·Journal of Pediatric Gastroenterology and Nutrition·Susan E CaudleValérie McLin
May 16, 2012·Nutritional Neuroscience·R C A GuedesRanilson de Souza Bezerra
Mar 15, 2013·Journal of Korean Medical Science·Hye Soo YooWon Soon Park
Sep 11, 2013·The American Journal of Tropical Medicine and Hygiene·Laura C SimaMenachem Elimelech
Aug 27, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Lucia MarsegliaGuido Moro
Oct 7, 2015·Journal of Biosocial Science·Visalakshi JeyaseelanBijesh Yadav
Nov 5, 2016·Environmental Health : a Global Access Science Source·Kelsey M GleasonMaitreyi Mazumdar
Dec 3, 2016·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Sumithra SelvamKrishnamachari Srinivasan
Aug 7, 2019·Nutrients·Andrew L Thorne-LymanLaurie C Miller
Aug 25, 2020·Maternal & Child Nutrition·Jessica L BlankenshipHedy Ip
Sep 30, 2000·The American Journal of Clinical Nutrition·Y WangB M Popkin
Nov 29, 2001·Lipids·R UauyE E Birch
Aug 31, 2001·European Journal of Clinical Nutrition·A HallUNKNOWN Partnership for Child Development
Apr 23, 2005·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Eric Taylor, Jody Warner Rogers
Mar 26, 2003·Pediatric Transplantation·Kevin KrullEstella Alonso
Feb 9, 2008·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·R R Faden, M Powers
Feb 19, 2008·Cadernos de saúde pública·Letícia Marques dos SantosMauricio L Barreto
Jan 20, 2012·International Journal of Epidemiology·Gwenyth LeeMargaret Kosek
Oct 30, 2009·Journal of Perinatology : Official Journal of the California Perinatal Association·J TrintisS Aucott
Aug 3, 2011·Maternal & Child Nutrition·Alemtsehay BogaleK Michael Hambidge
Oct 23, 2010·Obstetrics and Gynecology·Kathleen M RasmussenAnna Maria Siega-Riz
Sep 21, 2011·Journal of Tropical Pediatrics·May F NassarAhmad E Abdel-Mobdy
Apr 17, 2014·The Cochrane Database of Systematic Reviews·Rebecca LangfordRona Campbell
Aug 26, 2014·Paediatrics and International Child Health·Jessica MacIntyreDavid M Goldfarb
May 22, 2002·Public Health Nutrition·Therese HeskethAndrew M Tomkins

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.