A review of the complexity of biology of lymphatic filarial parasites

Journal of Parasitic Diseases : Official Organ of the Indian Society for Parasitology
K P PailyP K Das

Abstract

There are about five more common, including Wuchereria bancrofti and Brugia malayi, and four less common filarial parasites infecting human. Genetic analysis of W. bancrofti populations in India showed that two strains of the species are prevalent in the country. The adult filarial parasites are tissue specific in the human host and their embryonic stage, called microfilariae (mf), are found in the blood or skin of the host, depending upon the species of the parasite. Three genetically determined physiological races exist in W. bancrofti and B. malayi, based on the microfilarial periodicity. They are the nocturnally periodic, nocturnally subperiodic and diurnally subperiodic forms. The susceptibility of a mosquito species to filarial infection depends on various factors, which could be genetic, physiological or physical. Survival analysis of Culex quinquefasciatus infected with W. bancrofti showed that the parasite load in the mosquito is a risk factor of vector survival. The extrinsic life cycle of the parasite is initiated when the mf are ingested by a mosquito vector during feeding on the host blood. On maturity, most of the infective L3 stage larvae migrate to the head and proboscis of the mosquito to get transmitted to the...Continue Reading

References

Jan 1, 1979·The American Journal of Tropical Medicine and Hygiene·J H CrossS Oemijati
Jan 1, 1979·The American Journal of Tropical Medicine and Hygiene·B Carme, J Laigret
Jul 1, 1990·The American Journal of Tropical Medicine and Hygiene·W RiberuJ K Baird
Apr 1, 1988·Annals of Tropical Medicine and Parasitology·C C Chen, C M Shih
Sep 1, 1987·The American Journal of Tropical Medicine and Hygiene·E D FrankeI Wiady
Jun 1, 1986·Annals of Tropical Medicine and Parasitology·V Zaman, E Narayanan
Dec 1, 1971·Annals of Tropical Medicine and Parasitology·B A Obiamiwe, W W Macdonald
Jan 1, 1970·Transactions of the Royal Society of Tropical Medicine and Hygiene·B W Gooneratne, A B Sen
Jan 1, 1967·Transactions of the Royal Society of Tropical Medicine and Hygiene·F Hawking, J B Clark
Oct 22, 1983·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·R M May, R M Anderson
Jun 1, 1984·Journal of Helminthology·A B ReddyD Subrahmanyam
Dec 1, 1994·International Journal for Parasitology·W C Clark
Mar 1, 1995·Transactions of the Royal Society of Tropical Medicine and Hygiene·S C TewariR Reuben
Nov 1, 1995·Molecular and Biochemical Parasitology·M SironiC Genchi
Dec 16, 1998·Molecular and Biochemical Parasitology·K Henkle-DührsenR D Walter
Jan 28, 1999·Proceedings. Biological Sciences·C BandiM L Blaxter
Sep 24, 2002·Experimental Parasitology·Ramakrishna U RaoGary J Weil
Jun 21, 2003·Filaria Journal·Helen F McGarryMark J Taylor
Jul 1, 1957·Transactions of the Royal Society of Tropical Medicine and Hygiene·J F EDESON, R H WHARTON
May 1, 1960·Transactions of the Royal Society of Tropical Medicine and Hygiene·J F EDESONA B LAING
Mar 1, 1965·The American Journal of Tropical Medicine and Hygiene·A EWERT
Jun 1, 1965·Annals of Tropical Medicine and Parasitology·H L DAVID, J F EDESON
Apr 1, 1960·Annals of Tropical Medicine and Parasitology·A B LAINGR H WHARTON
Dec 1, 1951·Transactions of the Royal Society of Tropical Medicine and Hygiene·F HAWKING, J P THURSTON
May 17, 2006·Trends in Ecology & Evolution·Katelyn Fenn, Mark Blaxter

Citations

Dec 4, 2012·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Samantha N McNultyPeter U Fischer
Nov 1, 2016·Scientific Reports·Katherine GleaveLisa J Reimer
Oct 27, 2015·PLoS Neglected Tropical Diseases·Andrea M BinneboseBryan H Bellaire
Apr 21, 2016·PLoS Neglected Tropical Diseases·Nils PilotteSteven A Williams
Feb 18, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Jonathon P SchuldtSahara E Byrne
May 12, 2019·Molecular Biology and Evolution·Scott T SmallPeter A Zimmerman
Mar 20, 2020·The American Journal of Tropical Medicine and Hygiene·Anand Odedra, J S McCarthy
Jan 11, 2019·Microbiology and Molecular Biology Reviews : MMBR·Aislinn D Rowan-NashPeter Belenky
Mar 13, 2021·Journal of Medical Entomology·Annette KleinFanny Naccache

Related Concepts

Blood
Embryo
Filariasis
Head
Larva
Microfilaria
Culicidae
Parasites
Racial Group
Survival Analysis

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