PMID: 7023845Jun 1, 1981Paper

A review of the magnetic resonance response of biological tissue and its applicability to the diagnosis of cancer by NMR radiology

The Journal of Computed Tomography
D G Taylor, C F Bore

Abstract

It is now possible to produce cross-sectional NMR images of humans on a routine basis (52-54). Furthermore, there is a growing body of evidence from studies in vitro indicating that cancerous tissue has a significantly different NMR response from healthy tissue. Provided sufficient knowledge of the density, relaxation times, and their interrelation is available, then the technique of NMR radiology may with care be optimized to give considerable improvement over existing techniques in soft tissue discrimination and tumor detection. However, the first-order correlation of relaxation times with water density does raise the question of the uniqueness of diagnosis. Furthermore, the extrapolation of in vitro measurements to the situation in vivo is seen to be complicated by such factors as blood content, muscle and fluid motion, contributions from fat, and fluid in tissue spaces. Considerable study is required in vivo to resolve these uncertainties.

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Citations

May 1, 1992·Clinical Radiology·S F KeevilM A Smith
Jun 1, 1983·The British Journal of Ophthalmology·I MoseleyC Mills
Jul 1, 1989·American Journal of Otolaryngology·D E DawsonL Vaickus
Nov 22, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Paul BaronLambertus W Bartels
Jan 1, 1987·Magnetic Resonance Imaging·A Leroy-WilligA Louvel
Mar 1, 1984·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G M BydderI R Young
Dec 1, 1986·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G NavonG Valensin
Feb 1, 1989·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·M BrauerD L Foxall
Jun 1, 1988·Physics in Medicine and Biology·D G TaylorM C Bushell
May 1, 1984·Gut·P A Farrands, J D Hardcastle
Feb 22, 1992·BMJ : British Medical Journal·F D HobbsR Holder
Nov 27, 1986·The New England Journal of Medicine·E T FosselJ McDonagh

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