A review of the short- and long-term impact of weight loss on appetite in youth: what do we know and where to from here?

The Proceedings of the Nutrition Society
Helen TrubyCatia Martins

Abstract

This review seeks to synthesise our knowledge about changes in hunger and satiety that occur during diet-induced weight loss and during weight loss maintenance, with a particular focus on youth with obesity. Mechanisms of appetite responses to weight loss rely heavily on the adult literature. Physiological mechanisms that control appetite and satiety via the gut-brain axis have been elucidated but we have an incomplete picture of changes in gut hormones and peptides in youth with obesity. In adolescents, the role of the brain in long-term sensing of body composition and modifying appetite and satiety changes is easily over-ridden by hedonic influences for the reward of highly palatable sweet foods and encourages over-consumption. Accordingly, reward cues and hyper-responsiveness to palatable foods lead to a pattern of food choices. Different reward systems are necessary that are substantial enough to reward the continued individual effort required to sustain new behaviours, that need to be adopted to support a reduced body weight. Periods of growth and development during childhood provide windows of opportunity for interventions to influence body weight trajectory but long-term studies are lacking. More emphasis needs to be pla...Continue Reading

References

Mar 9, 1995·The New England Journal of Medicine·R L LeibelJ Hirsch
Mar 1, 1997·The American Journal of Clinical Nutrition·A G DullooL Girardier
Sep 16, 1999·The New England Journal of Medicine·I S FarooqiS O'Rahilly
Nov 15, 2001·Obesity Research·J E Blundell, A Gillett
Mar 1, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Michael RosenbaumRudolph L Leibel
Apr 9, 2004·The Journal of Clinical Endocrinology and Metabolism·Eric DoucetMary-Ellen Harper
Oct 19, 2004·American Journal of Preventive Medicine·Penny Gordon-LarsenBarry M Popkin
Jan 19, 2005·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·K Elfhag, S Rössner
Sep 15, 2005·International Journal of Obesity : Journal of the International Association for the Study of Obesity·M MarsF J Kok
Mar 12, 2008·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A S SinghM J M Chinapaw
Jul 12, 2008·Journal of Applied Physiology·Francesca AmatiBret H Goodpaster
Apr 25, 2009·Obesity·Arlette SantacruzUNKNOWN EVASYON Study Group
Sep 30, 2009·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·David H Zald
Nov 6, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rochelle GoldsmithMichael Rosenbaum
Jan 13, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·K N ManolopoulosK N Frayn
May 19, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J L KraschnewskiC N Sciamanna
May 28, 2010·The American Journal of Clinical Nutrition·Lauren B ShomakerJack A Yanovski
Mar 10, 2011·International Journal of Obesity : Journal of the International Association for the Study of Obesity·T A AjslevT Jess
Apr 19, 2011·Physiology & Behavior·Marc-Andre Cornier
Aug 30, 2011·Lancet·Boyd A SwinburnSteven L Gortmaker
Oct 28, 2011·The New England Journal of Medicine·Priya SumithranJoseph Proietto
Jun 9, 2012·Physiology & Behavior·Rebecca BoulosRobin B Kanarek
Oct 31, 2012·The British Journal of Nutrition·Margriet S Westerterp-PlantengaKlaas R Westerterp
Nov 7, 2012·Clinical Science·Priya Sumithran, Joseph Proietto
Dec 19, 2012·Medicine and Science in Sports and Exercise·Catia MartinsJohn E Blundell
Mar 29, 2013·The American Journal of Clinical Nutrition·Stefan G J A CampsKlaas R Westerterp
May 2, 2013·European Journal of Clinical Nutrition·P SumithranJ Proietto
Jun 5, 2013·Sleep·Dean W BeebeLawrence M Dolan
Aug 6, 2013·Physiology & Behavior·Christopher N OchnerF Xavier Pi-Sunyer
Dec 18, 2013·Obesity Research & Clinical Practice·Kimberley A BaxterHelen Truby
Feb 20, 2014·Sports Medicine·David Thivel, Jean-Philippe Chaput
Nov 18, 2014·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A A GibsonA Sainsbury
Dec 3, 2014·The Lancet. Diabetes & Endocrinology·Katrina PurcellJoseph Proietto
Apr 22, 2015·International Journal of Obesity : Journal of the International Association for the Study of Obesity·F L Greenway
Oct 16, 2015·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Katy Horner, SoJung Lee

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