A Review of the Use of Topical Calendula in the Prevention and Treatment of Radiotherapy-Induced Skin Reactions

Antioxidants
Joyson Kodiyan, Kyle T Amber

Abstract

Calendula is a topical agent derived from a plant of the marigold family Calendula Officinalis. Containing numerous polyphenolic antioxidants, calendula has been studied in both the laboratory and clinical setting for the use in treating and preventing radiation induced skin toxicity. Despite strong evidence in the laboratory supporting calendula's mechanism of action in preventing radiation induced skin toxicity, clinical studies have demonstrated mixed results. In light of the controversy surrounding the efficacy of calendula in treating and preventing radiodermatitis, the topic warrants further discussion.

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Citations

Feb 23, 2019·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Serena OliveriGabriella Pravettoni
Feb 27, 2020·Journal of Cosmetic Dermatology·Julie K NguyenJared Jagdeo
Jun 12, 2020·The International Journal of Lower Extremity Wounds·Georgios KoukourakisDimitrios Kardamakis
Jul 9, 2020·Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners·Diva SilvaIsabel F Almeida
Sep 24, 2020·The Australasian Journal of Dermatology·Shihab SiddiqueeMichael Penniment
Oct 11, 2017·Alternatives to Laboratory Animals : ATLA·Christa RaakThomas Ostermann
Sep 29, 2015·International Journal of Palliative Nursing·Joyson Kodiyan, Kyle T Amber
Jan 29, 2021·Advanced Healthcare Materials·Jiani XieYuliang Zhao
Oct 17, 2020·Oncology Nursing Forum·Tracy GosselinRebecca L Morgan

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Methods Mentioned

BETA
electron paramagnetic resonance

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