A Review of Transcranial Magnetic Stimulation as a Treatment for Post-Traumatic Stress Disorder

Current Psychiatry Reports
Caroline ClarkGeoffrey Grammer

Abstract

Patients with post-traumatic stress disorder (PTSD) may fail to achieve adequate relief despite treatment with psychotherapy, pharmacotherapy, or complementary medicine treatments. Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation procedure that can alter neuronal activity through administration of various pulse sequences and frequencies. TMS may theoretically have promise in correcting alterations observed in patients with PTSD. While the precise treatment location and pulse sequences remain undefined, current evidence suggests two promising targets, the right dorsolateral prefrontal cortex and the medial prefrontal cortex. The beneficial effects may be due to the secondary or indirect regulation of other brain structures that may be involved in the mood regulatory network. TMS may be an effective part of a comprehensive treatment program for PTSD, although significant work remains to define optimal treatment parameters and clarify how it fits within a broader traditional treatment program.

References

Mar 24, 1998·Archives of General Psychiatry·U D McCannR M Post
Aug 3, 2002·The Journal of Neuropsychiatry and Clinical Neurosciences·Paul B RosenbergMarshall Balish
May 16, 2006·Trends in Cognitive Sciences·Richard J McNally
Jul 21, 2007·Neuron·Mark Hallett
May 6, 2008·Journal of Anxiety Disorders·Elizabeth A OsuchUna McCann
Apr 17, 2009·Biological Psychiatry·Simone RossiMonica Ulivelli
Sep 11, 2009·Journal of Traumatic Stress·Lisa M Shin, Kathryn Handwerger
Jul 28, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Nadia Bolognini, Tony Ro
Sep 12, 2013·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Dong-Hyun NamJeong-Ho Chae
Mar 29, 2014·Journal of Evidence-based Complementary & Alternative Medicine·Helané WahbehJulien Cayton

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Citations

Jan 31, 2019·Annual Review of Clinical Psychology·Lauren A M LeboisKerry J Ressler
Apr 10, 2018·Frontiers in Neuroscience·Bhedita J SeewooJennifer Rodger
Dec 6, 2018·Frontiers in Behavioral Neuroscience·Monika M StojekSheila A M Rauch
Apr 5, 2019·Science Translational Medicine·Amit EtkinRuth O'Hara
Jun 22, 2017·The New England Journal of Medicine·Arieh ShalevCharles Marmar
Dec 17, 2017·Biological Psychiatry·Tommi RaijMohammed R Milad
Jan 15, 2019·Psychiatry Research·F Andrew KozelGlenn Catalano
May 4, 2021·Journal of Affective Disorders·Adam Harris, John Reece
Jun 15, 2021·Expert Opinion on Pharmacotherapy·Ansab Akhtar, Sangeeta Pilkhwal Sah

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