A review on the latest advances in extraction and analysis of artemisinin

Phytochemical Analysis : PCA
Lutfun NaharSatyajit D Sarker

Abstract

Artemisinin (1), a well-known natural antimalarial drug, is a sesquiterpene lactone that contains a unique peroxide bridge. Since its discovery, the amount of research into the analysis of artemisinin has increased considerably, and it has been further intensified since the Noble Prize win by Tu Youyou in the year 2015 for the discovery of artemisinin. To review literature on the extraction and analysis of artemisinin, published during 2017-present, and to present an appraisal of those methods. Extensive literature search was carried out which involved, but not limited to, the use of, various databases, like Web of Knowledge, PubMed and Google Scholar, and relevant published materials including published books. The keywords used, in various combinations, with artemisinin being present in all combinations, in the search were artemisinin, Artemisia annua, analysis, extraction, quantitative, qualitative and quality control. During the period covered in this review, several methods of analysis of artemisinin have been reported, the most of which were liquid chromatography (LC)-based methods. However, the use of new methods like near-infrared analysis, fluorometirc analysis and molecular imprinting, and a significant increase in the...Continue Reading

References

Feb 24, 2009·Journal of Pharmaceutical and Biomedical Analysis·Alexei A LapkinSmain Chemat
Mar 1, 2012·Methods in Molecular Biology·Lutfun Nahar, Satyajit D Sarker
Oct 22, 2015·FEMS Microbiology Letters·Rich Boden
Jan 19, 2016·Trends in Parasitology·Nicholas J WhiteFrançois H Nosten
Mar 5, 2016·Chemical Society Reviews·Lingxin ChenJinhua Li
Mar 1, 2017·Angewandte Chemie·Eduardo Troche-PesqueiraArmando Navarro-Vázquez
Jun 24, 2017·Medicinal Research Reviews·Yin Kwan WongJigang Wang
Aug 19, 2017·The American Journal of Tropical Medicine and Hygiene·Suqin GuoLiwang Cui
Sep 22, 2018·Journal of Pharmaceutical and Biomedical Analysis·Tianming DaiRenke Dai
Apr 21, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jiaqi RuanManyuan Wang

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