A Review on the Weight-Loss Effects of Oxidized Tea Polyphenols

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Dylan O'Neill RothenbergLingyun Zhang

Abstract

The mechanistic systems in the body through which tea causes weight loss are complex and multi-dimensional. Additionally, the bioactive components in tea such as catechins, caffeine, and products of tea polyphenol oxidation vary greatly from one major tea type to the next. Green tea has been the primary subject of consideration for investigation into the preventative health effects of tea because it contains the highest levels of phenolic compounds and retains the highest antioxidant capabilities of any major tea type. However, recent research suggests decreasing body fat accumulation has little to do with antioxidant activity and more to do with enzyme inhibition, and gut microbiota interactions. This paper reviews several different tea polyphenol-induced weight-loss mechanisms, and purposes a way in which these mechanisms may be interrelated. Our original 'short-chain fatty acid (SCFA) hypothesis' suggests that the weight-loss efficacy of a given tea is determined by a combination of carbohydrate digestive enzyme inhibition and subsequent reactions of undigested carbohydrates with gut microbiota. These reactions among residual carbohydrates, tea polyphenols, and gut microbiota within the colon produce short-chain fatty acids,...Continue Reading

References

Oct 27, 2004·Proceedings of the National Academy of Sciences of the United States of America·Fredrik BäckhedJeffrey I Gordon
May 26, 2005·Journal of Agricultural and Food Chemistry·Masaaki NakaiYoshinobu Kiso
Nov 18, 2005·European Journal of Gastroenterology & Hepatology·Prem H ThurairajahGeoffrey Haydon
Jan 31, 2006·The British Journal of Nutrition·Jonathan M HodgsonKevin D Croft
Jun 29, 2006·European Journal of Clinical Nutrition·T-F HsuS Yamamoto
Jul 11, 2006·The Journal of Clinical Investigation·Yun Chau Long, Juleen R Zierath
Jul 27, 2006·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Xia Wen, Thomas Walle
Feb 3, 2007·Mini Reviews in Medicinal Chemistry·J-P ChaputA Tremblay
Feb 14, 2007·The Journal of Nutritional Biochemistry·Sung I Koo, Sang K Noh
Dec 2, 2008·Nature·Peter J TurnbaughJeffrey I Gordon
Mar 10, 2009·Trends in Endocrinology and Metabolism : TEM·Martina I Lefterova, Mitchell A Lazar
Apr 10, 2009·Clinical Nephrology·L KaramadoukisA J Williams
Nov 13, 2009·The American Journal of Clinical Nutrition·Olivia J PhungCraig I Coleman
Nov 21, 2009·Journal of Nutritional Science and Vitaminology·Tomonori UnnoAyumu Nozawa
Jan 7, 2010·Journal of Agricultural and Food Chemistry·Lee Wah KohDejian Huang
Jan 21, 2010·International Journal of Molecular Sciences·Thomas Walle
May 18, 2010·International Journal of Food Microbiology·Marco CandelaPatrizia Brigidi
Mar 4, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·R HurselM S Westerterp-Plantenga
Oct 31, 2012·Journal of Agricultural and Food Chemistry·Yoko YamashitaHitoshi Ashida
Feb 8, 2013·Journal of Agricultural and Food Chemistry·Xiuling ZhuXiaoxiong Zeng
Mar 5, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M MillionM Paul
May 17, 2014·Gut·Herbert Tilg, Alexander R Moschen
Sep 27, 2014·Current Opinion in Cell Biology·D Grahame Hardie
Nov 6, 2014·Hormone Molecular Biology and Clinical Investigation·H Leon Bradlow
Dec 20, 2014·Journal of Ethnopharmacology·Takashi SatohKazuhiro Watanabe
Mar 6, 2015·The Journal of Nutrition·Pilou L H R JanssensMargriet S Westerterp-Plantenga
Apr 30, 2015·Journal of Diabetes Research·Isabel Moreno-Indias, Francisco José Tinahones
Jul 18, 2015·Molecular Nutrition & Food Research·Yadong ZhongFrida Fåk

❮ Previous
Next ❯

Citations

Jun 5, 2019·Current Nutrition Reports·Matthias Van Hul, Patrice D Cani
Jan 8, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Caibi ZhouLingyun Zhang
Feb 28, 2020·World Journal of Gastroenterology : WJG·Shi-Tong WangLi-Xuan Sang
Jun 20, 2019·Nutrients·Dylan O'Neill Rothenberg, Lingyun Zhang
Feb 6, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mamoru Isemura
Dec 26, 2018·Expert Opinion on Drug Metabolism & Toxicology·Liping WangZhongqiu Liu
Nov 21, 2020·Journal of the American College of Nutrition·Saptadip Samanta
Dec 1, 2020·Obstetrics & Gynecology Science·Shaymaa Kadhim JasimAli Kadhim Alqurishi
Dec 11, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Murad N AbualhasanMunir Al-Atrash
Aug 20, 2020·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Priyankar Dey
May 17, 2021·Physiological Research·A V Sirotkin, A Kolesárová
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Shuzhen WangChi-Tang Ho

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.