A review on therapeutic potentials of Trigonella foenum graecum (fenugreek) and its chemical constituents in neurological disorders: Complementary roles to its hypolipidemic, hypoglycemic, and antioxidant potential

Nutritional Neuroscience
Saima ZameerMohd Akhtar

Abstract

The growing rate of neurological disorders is a major concern in today's scenario. Today's research is focusing on therapeutic interventions providing benefits in these disorders. Presently, drugs of natural origin have gained more interest for the treatment of central nervous system disorders for their efficacy and less/ no side effects. This review is emphasizing the cited roles of Trigonella foenum graecum (fenugreek) and its constituents in different neurological manifestations. A review of the literature, relevant to the role of fenugreek and its major constituents including saponins and alkaloids in different neurological aspects and in delineating the health benefits, was conducted. The cited research acknowledged that fenugreek and its constituents exert positive influence on neurological health. Few studies have reported the beneficial role of fenugreek and its constituents like trigonelline in pathological symptoms of Alzheimer's disease. Similarly, other studies evidenced the neuroprotective, antidepressant, antianxiety as well as modulatory effect on cognitive functions and Parkinson's disease. Large populations are the sufferers of the neurological disorders, pointing the need for investigation of such therapeutic ...Continue Reading

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Mar 9, 2019·Metabolic Brain Disease·Ibraheem HusainAbul Kalam Najmi
Aug 16, 2019·Metabolites·Simone RochfortJoe Panozzo
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Nov 16, 2021·Frontiers in Pharmacology·Félicien Mushagalusa KasaliAmon Ganafa Agaba

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