PMID: 6413647Jan 1, 1983Paper

A risk index for the prediction of the incidence of non-A, non-B posttransfusion hepatitis in open-heart surgery patients

Journal of Medical Virology
Y NagatsukaN Ishida

Abstract

Risk factors related to the occurrence of non-A, non-B posttransfusion hepatitis (PTH) were statistically analyzed in 204 patients (115 adults and 89 children) who received blood transfusion and extracorporeal circulation during open-heart surgery. The PTH incidence, irrespective of age or body weight, was affected by both transfusion volume and circulation time, ie, the incidence increased cumulatively with the increment of these two variables. Based upon such statistical analysis, a "PTH-risk index," from which one can objectively predict the probability of PTH, was devised by the summation of standardized transfusion volumes (Vs) and circulation time (Ts). As a result, a high correlation between the obtained PTH-risk index and actual incidence was found. The obtained straight regression line between PTH-risk index and the actual incidence rate enabled us to predict the incidence of PTH in open-heart surgery patients.

References

Mar 12, 1977·Lancet·J L DienstagP V Holland
Mar 4, 1978·Lancet·H J AlterH Popper
Apr 10, 1975·The New England Journal of Medicine·S M FeinstoneP V Holland
Dec 25, 1975·The New England Journal of Medicine·V M VillarejosM R Hilleman
Jul 1, 1977·Annals of Internal Medicine·J H HoofnagleR H Purcell
Jul 1, 1977·Annals of Internal Medicine·J D MeyersK K Holmes
Sep 1, 1975·The American Journal of the Medical Sciences·H J AlterR H Purcell
Mar 1, 1966·Journal of Bacteriology·G Henle, W Henle
Sep 1, 1966·The New England Journal of Medicine·J B Hanshaw
Apr 25, 1981·Lancet·R HopkinsT Brown
Apr 1, 1980·Klinische Wochenschrift·K GmelinJ Bommer
Jan 1, 1983·Journal of Medical Virology·H OhoriN Ishida
Jan 1, 1980·Journal of Medical Virology·K N TsiquayeA J Zuckerman

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