A robust electrical conductivity imaging method with total variation and wavelet regularization

Magnetic Resonance Imaging
Xiangdong SunWufan Chen

Abstract

This study aims to develop and evaluate a robust conductivity imaging method that combines total variation and wavelet regularization to enhance the accuracy of conductivity maps. The proposed approach is based on a gradient-based method. The central equation is derived from Maxwell's equation and describes the relationship between conductivity and the transceive phase. A linear system equation is obtained via a finite-difference method and solved using a least-squares method. Total variation and wavelet transform regularization terms are added to the minimization problem and solved using the Split Bregman method to improve reconstruction stability. The proposed approach is compared with conventional and gradient-based methods. Numerical simulations are performed to validate the accuracy of the developed method, and the effects of noise are determined. Phantom and in vivo experiments are conducted at 3 T to verify the clinical applicability of the proposed method. Numerical simulations show that the proposed method is more robust than other methods and can suppress the effects of noise. The quantitative conductivity value of the phantom experiment agrees with the measured value. The in vivo experiment results present a clear st...Continue Reading

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