A role for brassinosteroids in light-dependent development of Arabidopsis

J LiJoanne Chory


Although steroid hormones are important for animal development, the physiological role of plant steroids is unknown. The Arabidopsis DET2 gene encodes a protein that shares significant sequence identity with mammalian steroid 5 alpha-reductases. A mutation of glutamate 204, which is absolutely required for the activity of human steroid reductase, abolishes the in vivo activity of DET2 and leads to defects in light-regulated development that can be ameliorated by application of a plant steroid, brassinolide. Thus, DET2 may encode a reductase in the brassinolide biosynthetic pathway, and brassinosteroids may constitute a distinct class of phytohormones with an important role in light-regulated development of higher plants.


Oct 5, 1990·Journal of Molecular Biology·S F AltschulD J Lipman
Jan 1, 1994·Annual Review of Biochemistry·D W Russell, J D Wilson
Aug 1, 1993·The Plant Journal : for Cell and Molecular Biology·A Konieczny, F M Ausubel

❮ Previous
Next ❯


Jan 1, 2008·The Arabidopsis Book·Leónie Bentsink, Maarten Koornneef
Dec 18, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·D Friedrichsen, J Chory
Nov 1, 1996·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·A von Arnim, X W Deng
May 3, 2005·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Y-W NamH-B Zhang
Apr 10, 2013·Plant Cell Reports·Jingjie HaoShui-zhang Fei
Jan 25, 2008·Planta·Gregory M SymonsJames B Reid
Jul 8, 2011·Planta·Leeann E ThorntonMichael M Neff
Aug 1, 1996·Trends in Genetics : TIG·R Hooley
Dec 4, 2001·Phytochemistry·U Stündl, B Schneider
Nov 28, 2002·Phytochemistry·B Vidya Vardhini, S Seeta Ram Rao
Aug 1, 1997·Phytochemistry·J SchmidtG Adam
Jul 17, 1998·Phytochemistry·S FujiokaS Yoshida
May 10, 2000·Steroids·J A RamírezL R Galagovsky
Feb 15, 2001·Trends in Genetics : TIG·P W Becraft
Dec 29, 1998·Trends in Genetics : TIG·T Altmann
Jan 1, 1997·Trends in Cell Biology·S A BarnesN H Chua
Aug 27, 1999·Trends in Plant Science·T Asami, S Yoshida
Feb 22, 2002·Current Opinion in Plant Biology·Joe Chappell
Mar 6, 1999·Current Opinion in Plant Biology·T Altmann
Mar 6, 1999·Current Opinion in Plant Biology·K LeaseJ C Walker
Feb 19, 2000·Current Opinion in Plant Biology·K Schumacher, J Chory
Jun 13, 2002·Physiologia Plantarum·Gregory M SymonsJames B Reid
Mar 12, 2008·Cell Research·Weihui XuYonghong Wang
May 16, 2006·Cell Research·Zhi-Yong WangChengguo Jia
Oct 6, 1997·The EMBO Journal·A C Mustilli, C Bowler
Feb 1, 1997·Natural Product Reports·S Fujioka, A Sakurai
Jan 1, 2003·Molecular Plant Pathology·Venkatappa K TharaJian-Min Zhou
Oct 26, 2001·Plant, Cell & Environment·K M RamonellM E Musgrave

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.