PMID: 8943147Nov 12, 1996Paper

A role for erythrocyte band 3 degradation by the parasite gp76 serine protease in the formation of the parasitophorous vacuole during invasion of erythrocytes by Plasmodium falciparum

Molecular and Biochemical Parasitology
E RoggwillerC Braun Breton

Abstract

A purified Plasmodium falciparum serine protease (gp76) implicated in erythrocyte invasion, degrades human erythrocyte band 3 and glycophorin A. Inhibition studies using synthetic peptides derived from the presumed band 3 enzymatic cleavage sites and the observed uptake of fluorescent phospholipids following gp76 treatment, suggest that band 3 degradation by this serine protease participates in the formation of the parasitophorous vacuole by restructuring the red cell cytoskeleton. These results provide a rationale for the elaboration of specific inhibitors to block red cell invasion by malaria parasites.

References

Feb 1, 1978·Annals of Tropical Medicine and Parasitology·G PasvolJ Brown
Oct 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·C B BretonL H Pereira da Silva
Nov 1, 1992·Biochemical Society Transactions·J C PinderW B Gratzer
Nov 1, 1992·Biochemical Society Transactions·N Mohandas
Oct 1, 1990·Research in Immunology·C Braun BretonL H Pereira da Silva
Nov 15, 1991·European Journal of Biochemistry·T BrinkmannH Tschesche
Aug 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·R B MikkelsenR Schmidt-Ullrich
Jul 1, 1986·Molecular and Biochemical Parasitology·C Braun-BretonL Pereira da Silva
Dec 1, 1986·Experimental Parasitology·A R DluzewskiW B Gratzer
Apr 20, 1967·Biochemical and Biophysical Research Communications·I Schechter, A Berger
Nov 30, 1993·Biochemistry·W Rodgers, M Glaser
Mar 1, 1993·Parasitology Today·C Braun Breton, L H Pereira da Silva

❮ Previous
Next ❯

Citations

Jul 30, 2010·Parasitology Research·Raquel Elisa da Silva-LópezSalvatore Giovanni de Simone
Nov 9, 2000·Molecular and Biochemical Parasitology·P RaphaelM Hanspal
Sep 12, 2001·Molecular and Biochemical Parasitology·M J Blackman, L H Bannister
Jun 22, 2002·Molecular and Biochemical Parasitology·Ashima KushwahaVirander S Chauhan
Apr 23, 2003·Molecular and Biochemical Parasitology·Cheryl-Ann LoboSara Lustigman
Sep 25, 1998·Molecular and Biochemical Parasitology·E RoggwillerC Braun Breton
Nov 7, 1999·Molecular and Biochemical Parasitology·F HackettM J Blackman
Apr 17, 2009·Nature Reviews. Microbiology·Alexander G MaierLeann Tilley
Apr 7, 2007·Current Opinion in Hematology·Didier DhermyMarie-Christine Lecomte
Jun 5, 2002·Annual Review of Biochemistry·Michael Klemba, Daniel E Goldberg
Aug 30, 2008·Malaria Journal·Sonja B Lauterbach, Theresa L Coetzer
Aug 1, 2012·PloS One·Hon Kuan DengMuriel Vayssier-Taussat
Mar 21, 1998·Emerging Infectious Diseases·P J Rosenthal
Feb 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·L H Bannister
May 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·J C BaraleG Langsley
Apr 15, 2003·Proceedings of the National Academy of Sciences of the United States of America·Vikas K GoelSteven S Oh
May 29, 2007·Parasitology Research·Herbert Leonel de Matos GuedesSalvatore Giovanni de Simone
Dec 13, 2007·Parasitology Research·Herbert Leonel de Matos GuedesSalvatore Giovanni De-Simone
Sep 2, 2004·Cellular Microbiology·Michael J Blackman
Jul 17, 2007·Molecular Microbiology·Jayasree IyerPeter R Preiser
Aug 10, 2005·Veterinary Parasitology·Brian M CookeRoss L Coppel
Jun 16, 2005·Experimental Parasitology·Minerva Paola Barrios-CeballosFelipe Padilla-Vaca
Jul 2, 2011·British Journal of Haematology·Elizabeth S Zuccala, Jake Baum
Sep 29, 2015·International Journal of Peptides·Cesar Henriquez-CamachoCiro Maguiña
Jul 31, 2012·Journal of Proteomics·Sukumar PonnusamyMahesh Choolani
Mar 31, 2012·Experimental Parasitology·Fuyuki TokumasuRick M Fairhurst
Aug 23, 2005·Memórias do Instituto Oswaldo Cruz·José Andrés Morgado-DíazSalvatore Giovanni De Simone
Sep 10, 2005·Biochimica Et Biophysica Acta·Hélène GuizouarnFranck Borgese
Jan 12, 2020·The Journal of Eukaryotic Microbiology·Edel Pérez-LópezPeta C Bonham-Smith
Nov 14, 2003·The Journal of Biological Chemistry·Agnieszka E TopolskaRoss L Coppel
Sep 6, 2019·Microbiology and Molecular Biology Reviews : MMBR·Jan D Warncke, Hans-Peter Beck
May 29, 1999·Antimicrobial Agents and Chemotherapy·V ConseilJ F Dubremetz
Apr 9, 2004·Seminars in Hematology·Brian M CookeRoss L Coppel
Sep 15, 2004·Experimental Parasitology·Raquel Elisa da Silva-Lopez, Salvatore Giovanni-De-Simone

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.