A rubella epidemic in an unvaccinated pregnant population. I. Screening methods and serological results

Scandinavian Journal of Infectious Diseases
K SkaugB Stray-Pedersen

Abstract

During the 1974 rubella epidemic in Oslo, paired sera from 7781 pregnant women were examined for rubella-specific IgG antibodies using the single radial haemolysis (SRH) test. 12.4% of the women with seronegative in early pregnancy, with no significant variations between the different age groups. In the seropositive samples, there was a mean decrease in the rubella IgG concentration of about 30% during 22 gestational weeks. 53 seroconversions were found. In addition, 22 primary infections were detected by the demonstration of rubella specific IgM antibodies using an indirect immunofluorescence test. The persistence of the rubella IgM antibodies was examined and a large individual variation was found, from less than 1 month up to 4 months after onset of the disease. The serological techniques, particularly the SRH test, were found to be well suited for mass screening.

References

Jan 1, 1978·Journal of Clinical Pathology·B GeeP R Mortimer
Dec 1, 1977·The Journal of Hygiene·M ClarkeG C Schild
Jan 1, 1979·Scandinavian Journal of Infectious Diseases·B Stray-Pedersen, A M Lorentzen-Styr
Oct 7, 1977·Deutsche medizinische Wochenschrift·J LeidelH J Eggers
Jan 1, 1973·Annals of the Rheumatic Diseases·P V ShirodariaF Stanford
May 1, 1972·Journal of Chronic Diseases·F Ederer
May 1, 1967·Proceedings of the Society for Experimental Biology and Medicine·P E HalonenJ A Stewart
Feb 1, 1980·American Journal of Obstetrics and Gynecology·B Stray-Pedersen
Jan 1, 1981·Scandinavian Journal of Infectious Diseases·J C UlstrupM Kandhari

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Citations

Jun 17, 2015·Risk Analysis : an Official Publication of the Society for Risk Analysis·Kimberly M Thompson, Cassie L Odahowski
Jun 1, 1988·Revista de saúde pública·A A MachadoA D Campos
Jan 1, 1981·Scandinavian Journal of Infectious Diseases·J C UlstrupM Kandhari
Apr 29, 1983·Journal of Immunological Methods·J Steinmann, H J Marzock
Jan 1, 1983·Journal of Clinical Microbiology·P W Neumann, J M Weber

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