A Sandwich Azobenzene-diamide Dimer for Photoregulated Chloride Transport

Chemistry : a European Journal
Manzoor AhmedPinaki Talukdar

Abstract

There has been a tremendous evolution for artificial ion transport systems, especially gated synthetic systems, which closely mimic their natural congeners. Herein, we demonstrate a trans -azobenzene based photo-regulatory anionophoric system that transports chloride by forming a sandwich dimeric complex. Further studies confirmed a carrier-mediated chloride-anion antiport mechanism, and the supramolecular interactions involved in chloride recognition within the sandwich complex were revealed from theoretical studies. Reversible trans-cis photoisomerization of the azobenzene was achieved without any significant contribution from the thermal cis → trans isomerization. Photoregulatory transport activity across the lipid bilayer membrane inferred an outstanding off-on response of the azobenzene photo-switch.

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Citations

Sep 15, 2021·Organic Letters·Manzoor AhmadPinaki Talukdar
Oct 8, 2021·Organic & Biomolecular Chemistry·Aidan KerckhoffsMatthew J Langton

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