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A Scalable Formulation for Engineering Combination Therapies for Evolutionary Dynamics of Disease

bioRxiv

Nov 7, 2013

Vanessa JonssonRichard M. Murray

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Abstract

It has been shown that optimal controller synthesis for positive systems can be formulated as a linear program. Leveraging these results, we propose a scalable iterative algorithm for the systematic design of sparse, small gain feedback strategies that stabilize the evolutionary dynamic...read more

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Mutant
Mutant Proteins
Antibodies, Neutralizing
Tissue Engineering
Research Study
Structure
HIV Therapy
Disease Theory of Alcohol or Other Drug Use, Abuse and Dependence
Disease Model
1
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  • A Scalable Formulation for Engineering Combination Therapies for Evolutionary Dynamics of Disease

    bioRxiv

    Nov 7, 2013

    Vanessa JonssonRichard M. Murray

    PMID: 990000075

    DOI: 10.1101/000075

    Abstract

    It has been shown that optimal controller synthesis for positive systems can be formulated as a linear program. Leveraging these results, we propose a scalable iterative algorithm for the systematic design of sparse, small gain feedback strategies that stabilize the evolutionary dynamic...read more

    Mentioned in this Paper

    Mutant
    Mutant Proteins
    Antibodies, Neutralizing
    Tissue Engineering
    Research Study
    1

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