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A Scalable Formulation for Engineering Combination Therapies for Evolutionary Dynamics of Disease

bioRxiv

Nov 7, 2013

Vanessa JonssonRichard M. Murray

Abstract

It has been shown that optimal controller synthesis for positive systems can be formulated as a linear program. Leveraging these results, we propose a scalable iterative algorithm for the systematic design of sparse, small gain feedback strategies that stabilize the evolutionary dynamic...read more

Mentioned in this Paper

Mutant Proteins
Antibodies, Neutralizing
Structure
Mutant
HIV Therapy
Tissue Engineering
Disease Theory of Alcohol or Other Drug Use, Abuse and Dependence
Disease Model
Research Study
1
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A Scalable Formulation for Engineering Combination Therapies for Evolutionary Dynamics of Disease

bioRxiv

Nov 7, 2013

Vanessa JonssonRichard M. Murray

PMID: 990000075

DOI: 10.1101/000075

Abstract

It has been shown that optimal controller synthesis for positive systems can be formulated as a linear program. Leveraging these results, we propose a scalable iterative algorithm for the systematic design of sparse, small gain feedback strategies that stabilize the evolutionary dynamic...read more

Mentioned in this Paper

Mutant Proteins
Antibodies, Neutralizing
Structure
Mutant
HIV Therapy
Tissue Engineering
Disease Theory of Alcohol or Other Drug Use, Abuse and Dependence
Disease Model
Research Study
1

Related Papers

Paper Details
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  • finger pointing at paper

    References currently unavailable

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