PMID: 1201610Dec 10, 1975Paper

A scanning electron microscopic study of the rat liver sinusoid: endothelial and Kupffer cells

Cell and Tissue Research
P Motta

Abstract

The surface ultrastructure of Kupffer cells in the rat liver has been studied by scanning electron microscopy (SEM). The results demonstrate that Kupffer cells are both significantly different and clearly distinct from endothelial cells. Kupffer cells have neither pores (and/or "sieve plates") nor fenestrations, all of which are present in endothelial cells. They possess a stellate shape, and only indirectly, with slender and irregular evaginations, contribute to the lining of the sinusoidal wall. Furthermore, the luminal surface in some areas contains a large population of short microvilli, microphicae and invaginations. These elements form a kind of microlabyrinth which may correpond to the "worm-like" structures described by transmission electron microscopy (TEM). In the present study, transition forms between endothelial and Kupffer cells were never found. On the contrary, considering the highly fenestrated nature of the endothelial cells, the Kupffer cells may, by ameboid movements, easily cross the overlapping barrier of the sinusoid and protrude into the lumen. Thus, acting as activated macrophages, the Kupffer cells might function to prevent the entrance of foreign material into the tissues of the liver through the frag...Continue Reading

Citations

Dec 7, 1976·Virchows Archiv. A, Pathological Anatomy and Histology·W NopanitayaM M Dotson
Jun 1, 1979·Biulleten' eksperimental'noĭ biologii i meditsiny·D N Maianskiĭ, S N Kutina
Mar 30, 2000·Journal of Anatomy·C CorsaroG Sichel
Apr 1, 1995·Alcoholism, Clinical and Experimental Research·T G SarphieN B D'Souza
Oct 23, 1998·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·T KondoK Messmer
May 14, 1979·Virchows Archiv. A, Pathological Anatomy and Histology·K Wegener, S Leipolz-Angermüller
Jul 12, 2002·Microscopy Research and Technique·Giovanni SichelConcetta Corsaro
Mar 1, 1990·Journal of Electron Microscopy Technique·R S McCuskey, P A McCuskey
Aug 1, 1983·The Anatomical Record·P L WrightR Fraser
Apr 1, 1978·The Anatomical Record·R Montesano, P Nicolescu
Jan 1, 1983·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·H FujitaK Yamashita
Jul 1, 1983·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A M de LeeuwD L Knook
Oct 29, 1976·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·H FrenzelH Hücker
May 1, 1984·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K M Mak, C S Lieber

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Obstetrics and Gynaecology of the British Empire
M M DAVIN-POWER, J P O'DWYER
Archivum Histologicum Japonicum = Nihon Soshikigaku Kiroku
M MutoT Fujita
Journal of Maxillofacial Surgery
R Roncevic
© 2022 Meta ULC. All rights reserved