A Scoping Insight on Potential Prophylactics, Vaccines and Therapeutic Weaponry for the Ongoing Novel Coronavirus (COVID-19) Pandemic- A Comprehensive Review.

Frontiers in Pharmacology
Priyanka DashBismita Nayak


The emergence of highly virulent CoVs (SARS-CoV-2), the etiologic agent of novel ongoing "COVID-19" pandemics has been marked as an alarming case of pneumonia posing a large global healthcare crisis of unprecedented magnitude. Currently, the COVID-19 outbreak has fueled an international demand in the biomedical field for the mitigation of the fast-spreading illness, all through the urgent deployment of safe, effective, and rational therapeutic strategies along with epidemiological control. Confronted with such contagious respiratory distress, the global population has taken significant steps towards a more robust strategy of containment and quarantine to halt the total number of positive cases but such a strategy can only delay the spread. A substantial number of potential vaccine candidates are undergoing multiple clinical trials to combat COVID-19 disease, includes live-attenuated, inactivated, viral-vectored based, sub-unit vaccines, DNA, mRNA, peptide, adjuvant, plant, and nanoparticle-based vaccines. However, there are no licensed anti-COVID-19 drugs/therapies or vaccines that have proven to work as more effective therapeutic candidates in open-label clinical trial studies. To counteract the infection (SARS-CoV-2), many pe...Continue Reading


Mar 1, 1984·Journal of Veterinary Pharmacology and Therapeutics·W C Campbell, G W Benz
Oct 5, 2001·Clinical Microbiology Reviews·C E Samuel
Mar 19, 2002·Antimicrobial Agents and Chemotherapy·Y FurutaK Shiraki
Aug 2, 2003·Lancet·J CinatlH W Doerr
Nov 1, 2003·The Lancet Infectious Diseases·Andrea SavarinoRoberto Cauda
May 18, 2004·Biochemical and Biophysical Research Communications·Norio YamamotoNaoki Yamamoto
Jun 9, 2004·Biochemical and Biophysical Research Communications·Kehu YuanHongkui Deng
Sep 8, 2004·Biochemical and Biophysical Research Communications·Els KeyaertsMarc Van Ranst
Aug 24, 2005·Virology Journal·Martin J VincentStuart T Nichol
Oct 18, 2005·Drugs·Caroline M PerryRisto S Cvetković
Jul 25, 2007·The Lancet Infectious Diseases·Nicholas J White
Apr 9, 2008·Current Medicinal Chemistry·Y S BoriskinS J Polyak
Nov 4, 2008·Current Opinion in Biotechnology·Jonathan M Gershoni
Apr 16, 2009·Clinical Microbiology Reviews·Jenefer M BlackwellDavid Burgner
Aug 21, 2009·Expert Opinion on Biological Therapy·Jae Woo LeeMichael A Matthay
Oct 20, 2009·Trends in Plant Science·Henry DaniellStephen J Streatfield
Mar 2, 2010·The Journal of Steroid Biochemistry and Molecular Biology·Peter J Barnes
Feb 16, 2011·Proceedings of the Japan Academy. Series B, Physical and Biological Sciences·Andy Crump, Satoshi Ōmura
Jul 15, 2011·The Journal of General Virology·Adriaan H de WildeMartijn J van Hemert
Nov 9, 2012·International Journal of Biological Sciences·Stefan Rose-John
Aug 13, 2013·The Lancet Infectious Diseases·Emmie de Wit, Vincent J Munster
Dec 17, 2014·The Journal of Biological Chemistry·Lin YuanLingqiang Zhang
Sep 9, 2015·Nature Biotechnology·Elvin BlancoMauro Ferrari
Nov 28, 2015·Rheumatic Diseases Clinics of North America·Sivapriya Ramamoorthy, John A Cidlowski
Dec 15, 2015·Cellular and Molecular Life Sciences : CMLS·Benoit Pasquier
Feb 13, 2016·Nature Reviews. Drug Discovery·Alimuddin ZumlaKwok-Yung Yuen
Oct 25, 2016·Trends in Microbiology·Diego ForniManuela Sironi
Dec 9, 2016·Expert Opinion on Drug Safety·C Ponticelli, G Moroni
Dec 23, 2016·Proceedings of the National Academy of Sciences of the United States of America·Rameshwar U Kadam, Ian A Wilson

❮ Previous
Next ❯


❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Epigenetics Insights from Twin Studies

Find the latest research on epigenetics and twin studies here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.

© 2021 Meta ULC. All rights reserved