Abstract
Seventy-seven plant extracts (corresponding to 62 different species) traditionally used by the Isoceño-Guaraní, a native community living in the Bolivian Chaco, were screened for antimalarial activity in vitro on Plasmodium falciparum chloroquine sensitive strain (F32), and on ferriprotoporphyrin (FP) IX biocrystallisation inhibition test (FBIT). Among these extracts, seven displayed strong in vitro antimalarial activity, and 25 were active in the FBIT test. Positive results on both tests were recorded for six extracts: Argemone subfusiformis aerial part, Aspidosperma quebracho-blanco bark, Castela coccinea leaves and bark, Solanum argentinum leaves and Vallesia glabra bark. Results are discussed in relation with Isoceño-Guaraní traditional medicine. Further studies to be undertaken in relation with these results are also highlighted.
References
Apr 1, 1979·Journal of Ethnopharmacology·R E Schultes
Aug 20, 1976·Science·W Trager, J B Jensen
Apr 1, 1992·Journal of Ethnopharmacology·M G BrandãoA U Krettli
Dec 1, 1991·Molecular and Biochemical Parasitology·S R MeshnickH Z Pan
Jan 1, 1991·Memórias do Instituto Oswaldo Cruz·C Z AmorimR S Cordeiro
May 1, 1991·Journal of Ethnopharmacology·S C ChhabraE N Mshiu
Dec 1, 1994·Journal of Ethnopharmacology·A Filipov
Nov 1, 1995·Phytochemistry·A ValentinJ M Bessière
Jan 1, 1996·Journal of Natural Products·J DouL A Walker
Jan 5, 2000·Journal of Ethnopharmacology·N P LopesA M Katzin
Feb 25, 2000·Journal of Ethnopharmacology·V MuñozE Deharo
Apr 5, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·F NoireauF Vargas
Mar 7, 2002·Parasitology International·N SriwilaijareonP Wilairat
May 9, 2002·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·A C Mitaine-OfferM Zèches-Hanrot
Jul 20, 2002·Experimental Parasitology·E DeharoH Ginsburg
May 4, 2004·Journal of Ethnopharmacology·G BourdyA Roca-Coulthard
Feb 1, 1995·Planta medica·M ZèchesL L Men-Olivier
Citations
Apr 9, 2005·Journal of Ethnopharmacology·M VigneronG Bourdy
May 3, 2007·Journal of Ethnobiology and Ethnomedicine·Alexandros S Botsaris
Jan 10, 2014·Memórias do Instituto Oswaldo Cruz·Julia Penna CoutinhoAntoniana Ursine Krettli
May 5, 2007·Natural Product Research·Jian-Guo JiangQing-Sheng Lin
May 4, 2010·Journal of Ethnopharmacology·P S WereH S Ozwara
Jun 10, 2009·Journal of Ethnopharmacology·Michael HeinrichMonique S J Simmonds
Dec 20, 2015·Malaria Journal·Renata B S LimaAdrian M Pohlit
Nov 14, 2006·Journal of Ethnopharmacology·M L de MesquitaL S Espindola
Oct 13, 2006·Journal of Ethnopharmacology·Abdolali MohagheghzadehYounes Ghasemi
Mar 7, 2006·Journal of Ethnopharmacology·L P KvistA Gonzalez
Nov 3, 2010·Journal of Ethnopharmacology·Lastenia RuizVincent Roumy
Sep 7, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Geethi PamunuwaViduranga Y Waisundara
Dec 5, 2012·Anais Da Academia Brasileira De Ciências·Maria Fâni DolabelaAlaide B Oliveira
Oct 3, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Immacolata FaraoneLuigi Milella
Mar 13, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Heloisa Alves GuimarãesIvo José Curcino Vieira
Oct 5, 2019·Biomolecules·Paula SainzAzucena González-Coloma
Mar 1, 2018·The Journal of Pharmacy and Pharmacology·Dayane P de AraújoGlauce S B Viana
Nov 28, 2018·Malaria Journal·Isabela P CeravoloAntoniana U Krettli
Oct 4, 2020·Applied Biochemistry and Biotechnology·Daniel A González-VelázquezJuan C Ramírez-Suarez
Nov 17, 2019·Food Research International·Gustavo Araujo PereiraGlaucia Maria Pastore