A second double-stranded RNA virus from yeast

Virology
C ParkJ A Bruenn

Abstract

Two double-stranded RNA viruses exist as permanent persistent infections of the yeast Saccharomyces cerevisiae: ScVL1 and ScVLa. Both belong to the Totiviridae, which include a number of fungal and protozoan double-stranded RNA viruses. Although ScVL1 and ScVLa share the same genomic organization and mode of expression and coexist in the same cells, they show no evidence of recombination: with one limited exception, sequence conservation is detectable only in regions conserved in all totiviruses. Both have two open reading frames on their single essential RNAs: cap (encoding a capsid polypeptide) and pol (encoding an RNA-dependent RNA polymerase). The ScVLa virus, like ScVL1, appears to express its Pol domain by a -1 translational frameshift.

Citations

Oct 29, 1996·Proceedings of the National Academy of Sciences of the United States of America·S Huang, S A Ghabrial
Aug 12, 2009·Eukaryotic Cell·A Carolin Frank, Kenneth H Wolfe
Jul 19, 2005·Proceedings of the National Academy of Sciences of the United States of America·Toru NakayashikiReed B Wickner
Aug 2, 2000·Proceedings of the National Academy of Sciences of the United States of America·A M Searfoss, R B Wickner
Jun 1, 1996·Molecular Microbiology·C M ParkJ A Bruenn
Oct 7, 2016·PLoS Pathogens·Paul A RowleySara L Sawyer
Jul 5, 2013·The Journal of Biological Chemistry·Tsutomu Fujimura, Rosa Esteban
Jan 28, 2021·Microorganisms·Lina AitmanaitėSaulius Serva
Mar 1, 1997·Journal of Virology·W YaoJ A Bruenn

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