A second signal for autophagic cell death?

Autophagy
Corinne GiustiPierre Golstein

Abstract

Dictyostelium cells in monolayers in vitro lend themselves well to a study of autophagic cell death (ACD). There is no apoptosis machinery in the protist Dictyostelium, no caspase nor Bcl-2 family members (except a paracaspase whose inactivation does not alter cell death), thus there is no apoptosis that could interfere with, or substitute for, nonapoptotic cell death. Also, Dictyostelium, a eukaryote, has a haploid genome, which facilitates random insertional mutagenesis.

Citations

Aug 9, 2008·American Journal of Respiratory Cell and Molecular Biology·Ralf H HubnerRonald G Crystal
Mar 25, 2014·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·V VinodSrinivas Gopala
Sep 27, 2014·Cell Death and Differentiation·Y Liu, B Levine
Oct 22, 2014·Immunology and Cell Biology·Donna DentonSharad Kumar
Jul 13, 2016·Current Biology : CB·Douglas R Green, Patrick Fitzgerald
Jun 3, 2017·Cell Death and Differentiation·Santosh K DasariAdi Kimchi
Sep 22, 2018·Journal of Cell Science·Shani BialikAdi Kimchi
Apr 4, 2021·Cells·Or CabassoMia Horowitz

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