A selectively deprotectable triazacyclophane scaffold for the construction of artificial receptors

Organic Letters
T Opatz, Rob M J Liskamp


[reaction: see text]. The synthesis of a triazacylclophane scaffold bearing a set of selectively removable protecting groups is described. This versatile scaffold, which can be linked to a solid support, allows the attachment of three different side chains and can therefore be used for the combinatorial synthesis of libraries of artificial receptor molecules of high structural diversity.



Jan 17, 2012·Journal of Medicinal Chemistry·Christopher J ArnuschYechiel Shai
Mar 26, 2008·Chemical Communications : Chem Comm·H Bauke AlbadaRob M J Liskamp
Feb 3, 2016·Frontiers in Bioengineering and Biotechnology·Andrea GroßJutta Eichler
Oct 22, 2008·Current Opinion in Chemical Biology·Jutta Eichler
Dec 17, 2016·Chembiochem : a European Journal of Chemical Biology·Helmus van de LangemheenRob M J Liskamp
Dec 4, 2014·Chembiochem : a European Journal of Chemical Biology·Linde E J SmeenkPeter Timmerman
Sep 22, 2007·Chembiochem : a European Journal of Chemical Biology·Dirk-Jan van ZoelenRob M J Liskamp
Apr 2, 2010·Organic & Biomolecular Chemistry·Seiji KamiokaTakayuki Doi
Aug 8, 2006·Chembiochem : a European Journal of Chemical Biology·Yashveer SinghPascal Dumy
Sep 14, 2012·Chemical Society Reviews·Zeyuan DongJunqiu Liu
Sep 1, 2012·Chemical Communications : Chem Comm·Gwenn E MulderRob M J Liskamp
Dec 29, 2020·Bioorganic Chemistry·Jan HajduchJiří Jiráček

Related Concepts

Alanylalanine, (L-Ala)-(DL-Ala)-isomer
Bacteriocidal Agents
Aza Compounds
High Pressure Liquid Chromatography Procedure
Polymorphism, Crystallization
Spectrophotometry, Ultraviolet

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.