A self-expanding bifurcated endovascular graft for abdominal aortic aneurysm repair. An initial study in a canine model

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
G J WilsonL Pinchuk

Abstract

Approximately 50,000 abdominal aortic aneurysms (AAAs) are surgically repaired annually in the United States. Endovascular grafts (EVGs) combine a stent and a vascular graft offering great potential for reduced morbidity, mortality, and hospital stay because of minimally invasive endoluminal placement through catheters. Because most AAAs extend into one or both iliac arteries, a bifurcated EVG (bEVG) was developed, consisting of a proximal aortic trunk divided into two distinct lumens or sockets to receive two smaller diameter leg (iliac) components. All components were composed of Didcott self-expanding braided wire stents integrally attached to porous spun polycarbonate urethane liners. Successful placement of the bEVGs (trunks 10-12 mm and legs 5-6 mm diameter) by a 10 Fr introducer through the femoral arteries into the infrarenal aorta and external iliac arteries of 9 of 11 dogs was achieved. Subsequently, 11 of 12 bEVGs were successfully placed to exclude a saccular aneurysm exceeding three aortic diameters created by a fascia lata pouch extending from the aorta into the left external iliac artery, of which 7 were patent at 1 to 4 months. These findings establish design feasibility of the bEVG as well as the utility of the...Continue Reading

Citations

May 19, 1998·Progress in Cardiovascular Diseases·D J Wirthlin, R P Cambria
Sep 24, 1999·Journal of Endovascular Surgery : the Official Journal of the International Society for Endovascular Surgery·R E BeyguiC K Zarins
Mar 7, 2015·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Yahya ElsayedChakravarthini M Saaj
Jul 3, 2015·Journal of Functional Biomaterials·Charanpreet SinghXungai Wang
Jul 1, 2006·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·R GuidoinR Guzman
Nov 6, 2007·Biomaterials·Leonard PinchukJoseph P Kennedy
Nov 7, 1999·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·I A BroedersB C Eikelboom
Nov 16, 2013·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Y GeorgUNKNOWN Groupe Européen de Recherche sur les Prothèses appliquées à la Chirurgie Vasculaire (GEPROVAS)
Mar 16, 2006·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·R GuidoinR Guzman

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