A semi-empirical model for flow or blood and other particulate suspensions through narrow tubes

Bulletin of Mathematical Biology
R N Das, V Seshadri

Abstract

A semi-empirical model applicable to the flow of blood and other particulate suspensions through narrow tubes has been developed. It envisages a central core of blood surrounded by a wall layer of reduced hematocrit. With the help of this model the wall layer thickness and extent of plug flow may be calculated using pressure drop, flow rate and hematocrit reduction data. It has been found from the available data in the literature that for a given sample of blood the extent of plug flow increases with decreasing tube diameter. Also for a flow through a given tube it increases with hematocrit. The wall layer thickness is found to decrease with increase in blood hematocrit. A comparison between the results of rigid particulate suspensions and blood reveals that the thicker wall layer and smaller plug flow radius in the case of blood may be attributed to the deformability of the erythrocytes.

References

Oct 1, 1969·Physiological Reviews·E W Errill
Oct 1, 1969·Microvascular Research·E K Greenwald
Mar 1, 1969·The Bulletin of Mathematical Biophysics·M M Lih
Feb 1, 1948·The Journal of Physical and Colloid Chemistry·V VAND

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