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A sensitive radioenzymatic assay for catechol drugs

Journal of Neuroscience Research

Jan 1, 1980

L R Durrett, M G Ziegler

Abstract

This assay measures picogram quantities of catechol drugs and endogenous catecholamines in body tissues and fluids. The catechols are converted to their 3H-O-methyl metabolites during incubation with 3H-S-adenosylmethionine then separated by solvent extraction and thin-layer chromatogra...read more

Mentioned in this Paper

Epinephrine Measurement
Norepinephrine Measurement
Assay
Body Fluids and Substances
Isoproterenol
Methylation
Norepinephrine
S-Adenosylmethionine
Drug or Chemical Tissue Distribution
Tritium
Paper Details
References
  • References5
  • Citations47
12345

A sensitive radioenzymatic assay for catechol drugs

Journal of Neuroscience Research

Jan 1, 1980

L R Durrett, M G Ziegler

PMID: 7205995

DOI: 10.1002/jnr.490050613

Abstract

This assay measures picogram quantities of catechol drugs and endogenous catecholamines in body tissues and fluids. The catechols are converted to their 3H-O-methyl metabolites during incubation with 3H-S-adenosylmethionine then separated by solvent extraction and thin-layer chromatogra...read more

Mentioned in this Paper

Epinephrine Measurement
Norepinephrine Measurement
Assay
Body Fluids and Substances
Isoproterenol
Methylation
Norepinephrine
S-Adenosylmethionine
Drug or Chemical Tissue Distribution
Tritium
Paper Details
References
  • References5
  • Citations47
12345
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