A septal angle measured on computed tomographic pulmonary angiography can noninvasively estimate pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension

Journal of Thoracic Imaging
Min LiuChen Wang

Abstract

To explore the correlation between a septal angle measured on computed tomographic pulmonary angiography (CTPA) and pulmonary vascular resistance (PVR) determined by right heart catheterization in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Eighty-six patients with CTEPH (54 men, mean age: 53.08±12.43 y) were retrospectively reviewed, and 86 sex-matched and age-matched individuals without pulmonary artery hypertension and pulmonary embolism were used as the control group. All patients with CTEPH underwent CTPA before right heart catheterization. Septal angle was measured on transverse CTPA images as the angle between the interventricular septum and the line joining the midpoint of the sternum to the thoracic vertebral spinous process. Hemodynamic PVR was calculated on the basis of the data from right heart catheterization. Septal angle was 65.27±12.24 degrees and 39.43±9.79 degrees in the CTEPH group and control group, respectively, which was statistically significant (t=18.139, P=0.000). The septal angle correlated positively with PVR (r=0.629, P=0.000). By stepwise linear regression analysis, the septal angle was shown to be the only variable (r=0.578) that was independently associated with PVR levels...Continue Reading

References

Sep 10, 2002·Journal of Computer Assisted Tomography·Sohail ContractorDevang M Gor
Jul 2, 2003·European Radiology·D CollombG Ferretti
Nov 7, 2003·The Annals of Thoracic Surgery·Stuart W JamiesonWilliam R Auger
May 10, 2005·The American Journal of Cardiology·Nicolas MansencalOlivier Dubourg

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Citations

Jul 16, 2015·The Clinical Respiratory Journal·Ruijuan SunErdan Dong
Dec 10, 2014·European Journal of Radiology·Andreas Gunter BachAlexey Surov
Jan 7, 2017·Journal of Thoracic Imaging·Rahul D RenapurkarDeepa Gopalan
Feb 18, 2020·European Radiology·Weifang LiuSheng Xie
Apr 29, 2020·European Radiology·Andrew J SwiftDavid G Kiely

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