A sex-role-preference model for HIV transmission among men who have sex with men in China.

BMC Public Health
Jie LouYiming Shao

Abstract

Men who have sex with men (MSM) are much more likely to be infected with HIV than the general population. China has a sizable population of MSM, including gay, bisexual men, money boys and some rural workers. So reducing HIV infection in this population is an important component of the national HIV/AIDS prevention and control program. We develop a mathematical model using a sex-role-preference framework to predict HIV infection in the MSM population and to evaluate different intervention strategies. An analytic formula for the basic reproduction ratio R0 was obtained; this yields R0 = 3.9296 in the current situation, so HIV will spread very fast in the MSM population if no intervention measure is implemented in a timely fashion. The persistence of HIV infection and the existence of disease equilibrium (or equilibria) are also shown. We utilized our model to simulate possible outcomes of antiretroviral therapy and vaccination for the MSM population. We compared the effects of these intervention measures under different assumptions about MSM behaviour. We also found that R0 is a decreasing function of the death rate of HIV-infected individuals, following a power law at least asymptotically. HIV will spread very fast in the MSM po...Continue Reading

References

Aug 15, 1996·Annals of Internal Medicine·M M DeschampsW D Johnson
Jan 24, 2004·Mathematical Biosciences·Sara Del ValleShu-Fang Hsu Schmitz
Apr 3, 2004·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Kyung-Hee ChoiYaqi Guo
May 3, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Ume L AbbasJohn W Mellors
Jul 1, 2006·Mathematical Biosciences and Engineering : MBE·Romulus BrebanSally Blower
Aug 9, 2011·BMJ : British Medical Journal·Bob Roehr
Feb 15, 2012·Asia-Pacific Journal of Public Health·Yupin JopangFrank Peter Schelp

❮ Previous
Next ❯

Citations

Jan 1, 2009·BMC Public Health·Robert J Smith, Richard Gordon
Dec 7, 2013·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·V CambianoM J van de Laar
Nov 7, 2013·BioMed Research International·Xiaodan SunNing Wang
Sep 21, 2011·European Journal of Epidemiology·Narat PunyacharoensinRichard Guy White
Jan 7, 2016·Journal of Biomedical Informatics·Nina B BaltierraLisa B Hightow-Weidman
Jun 25, 2015·AIDS Research and Human Retroviruses·Nittaya PhanuphakJean Louis Excler
Jan 19, 2016·Mathematical Biosciences and Engineering : MBE·Xiaodan SunZhihang Peng
Jun 18, 2016·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Xin ZengAilong Huang
Sep 16, 2015·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Jessie L Juusola, Margaret L Brandeau
Jan 1, 2013·Vaccines·Punnee PitisuttithumJean-Louis Excler
Dec 1, 2017·AIDS and Behavior·Beverley CummingsH Fisher Raymond

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.