A Shared Molecular and Genetic Basis for Food and Drug Addiction: Overcoming Hypodopaminergic Trait/State by Incorporating Dopamine Agonistic Therapy in Psychiatry

The Psychiatric Clinics of North America
Mark S GoldK Blum

Abstract

This article focuses on the shared molecular and neurogenetics of food and drug addiction tied to the understanding of reward deficiency syndrome. Reward deficiency syndrome describes a hypodopaminergic trait/state that provides a rationale for commonality in approaches for treating long-term reduced dopamine function across the reward brain regions. The identification of the role of DNA polymorphic associations with reward circuitry has resulted in new understanding of all addictive behaviors.

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Citations

Oct 10, 2019·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Eve H Limbrick-OldfieldLuke Clark
Jul 22, 2018·Psychopharmacology·Jennifer M MitchellAndrew S Kayser
Sep 15, 2018·Molecular Psychiatry·Luke ClarkMartin Zack
Jan 31, 2018·The Journal of the American Osteopathic Association·Dave BaronRajendra D Badgaiyan
Apr 17, 2021·Neuropharmacology·M Serafine KatherineZorrilla Eric P

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