A signal cascade originated from epidermis defines apical-basal patterning of Arabidopsis shoot apical meristems.

Nature Communications
Han HanYun Zhou

Abstract

In multicellular organisms, a long-standing question is how spatial patterns of distinct cell types are initiated and maintained during continuous cell division and proliferation. Along the vertical axis of plant shoot apical meristems (SAMs), stem cells are located at the top while cells specifying the stem cells are located more basally, forming a robust apical-basal pattern. We previously found that in Arabidopsis SAMs, the HAIRY MERISTEM (HAM) family transcription factors form a concentration gradient from the epidermis to the interior cell layers, and this gradient is essential for the stem cell specification and the apical-basal patterning of the SAMs. Here, we uncover that epidermis specific transcription factors, ARABIDOPSIS THALIANA MERISTEM LAYER 1 (ATML1) and its close homolog, define the concentration gradient of HAM in the SAM through activating a group of microRNAs. This study provides a molecular framework linking the epidermis-derived signal to the stem cell homeostasis in plants.

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Citations

Jul 30, 2020·Journal of Integrative Plant Biology·Lüwen ZhouYuling Jiao
Dec 19, 2020·Computational and Structural Biotechnology Journal·Ziyi LiuTian Hong
Feb 7, 2021·Plants·Hiroyuki Iida, Shinobu Takada
May 14, 2020·Trends in Plant Science·Jennifer C Fletcher
Jan 24, 2021·The Plant Journal : for Cell and Molecular Biology·Yuan GengYun Zhou
Mar 9, 2021·Journal of Experimental Botany·Kirtikumar R KondhareAnjan K Banerjee
Jun 22, 2021·Plant Signaling & Behavior·Yuan Geng, Yun Zhou

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Methods Mentioned

BETA
one hybrid
Y1H
electrophoresis
transgenic
genotyping
PCR
Assay

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