A simple and accurate formula to estimate left hepatic graft volume in living-donor adult liver transplantation

Transplantation
Noboru HaradaYoshihiko Maehara

Abstract

In the field of living-donor adult liver transplantation, a small-for-size graft often occurs, particularly when using left-lobe grafts. This is because of the limited volumes associated with left-lobe grafts. The accurate preoperative evaluation of graft volumes is crucial to avoid this complication. The aim of this study is to clarify the usefulness of a new formula to estimate the left-lobe graft volume. In 61 left-lobe grafts, a new formula was created with stepwise regression analysis using the following variables: height, weight, the thoracic and abdominal distance from anterior to posterior side (A-P), and distance from left to right side (L-R) of the initial 20 donors. With another 41 donors, the difference between the actual and estimated graft volume using the formula and two- and three-dimensional computed tomography was prospectively evaluated. On the basis of the results of the stepwise regression analysis, a new formula was created as follows: graft volume (ml) = 313.4 + 7.7 x weight (kg)-12.6 x thoracic L-R (cm). The difference between the actual and estimated graft volumes using the formula was significantly better (10.8 +/- 9.5%) than that of the volumetry using two-dimensional computed tomography (16.3 +/- 10....Continue Reading

References

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Citations

Nov 30, 2005·Transplantation·Paolo R O SalvalaggioMichael M Abecassis
Nov 12, 2013·The Surgical Clinics of North America·Lokesh BathlaAlan Langnas
Dec 17, 2009·Transplantation Proceedings·L Fu-GuiC Zhe-Yu
May 26, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J Michael Henderson
Mar 24, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Sander Florman, Charles M Miller
Aug 30, 2008·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Hiroto KayashimaYoshihiko Maehara
Nov 30, 2005·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Yusuke YonemuraYoshihiko Maehara
Mar 30, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Tetsuji YoneyamaYukihiro Inomata
Jan 22, 2014·Journal of Cellular Physiology·V PeriwalC Doria
Oct 31, 2015·Clinics and Research in Hepatology and Gastroenterology·Mohammad GolrizArianeb Mehrabi
May 15, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Haipeng MengLunan Yan

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